Evaluation of [<sup>68</sup>Ga]Ga-DOTA-TCTP-1 for the Detection of Metalloproteinase 2/9 Expression in Mouse Atherosclerotic Plaques

Evaluation of [<sup>68</sup>Ga]Ga-DOTA-TCTP-1 for the Detection of Metalloproteinase 2/9 Expression in Mouse Atherosclerotic Plaques

<i>Background</i>: The expression of matrix metalloproteinases 2/9 (MMP-2/9) has been implicated in arterial remodeling and inflammation in atherosclerosis. We evaluated a gallium-68 labeled peptide for the detection of MMP-2/9 in atherosclerotic mouse aorta. <i>Methods</i>:...

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Bibliographic Details
Main Authors: Max Kiugel, Sanna Hellberg, Meeri Käkelä, Heidi Liljenbäck, Tiina Saanijoki, Xiang-Guo Li, Johanna Tuomela, Juhani Knuuti, Antti Saraste, Anne Roivainen
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Molecules
Subjects:
atherosclerosis
imaging
matrix metalloproteinase
positron emission tomography
plaque
Online Access:https://www.mdpi.com/1420-3049/23/12/3168

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