Preoperative PROMIS Physical Function Scores Predict Postoperative Outcomes Following Total Ankle Replacement

Background: Despite good evidence that supports significant improvements in pain and physical function following a total ankle replacement (TAR) for end-stage ankle arthritis, there is a subset of patients who do not significantly benefit from surgery. The purpose of this study was to perform a prel...

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Main Authors: Matthew S. Conti MD, Kristin C. Caolo BA, Agnes D. Cororaton MS, Jonathan T. Deland MD, Constantine A. Demetracopoulos MD, Scott J. Ellis MD
Format: Article
Language:English
Published: SAGE Publishing 2021-07-01
Series:Foot & Ankle Orthopaedics
Online Access:https://doi.org/10.1177/24730114211020335
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author Matthew S. Conti MD
Kristin C. Caolo BA
Agnes D. Cororaton MS
Jonathan T. Deland MD
Constantine A. Demetracopoulos MD
Scott J. Ellis MD
author_facet Matthew S. Conti MD
Kristin C. Caolo BA
Agnes D. Cororaton MS
Jonathan T. Deland MD
Constantine A. Demetracopoulos MD
Scott J. Ellis MD
author_sort Matthew S. Conti MD
collection DOAJ
description Background: Despite good evidence that supports significant improvements in pain and physical function following a total ankle replacement (TAR) for end-stage ankle arthritis, there is a subset of patients who do not significantly benefit from surgery. The purpose of this study was to perform a preliminary analysis to determine if preoperative Patient-Reported Outcome Measurement Information System (PROMIS) scores could be used to predict which patients were at risk of not meaningfully improving following a TAR. Methods: Prospectively collected preoperative and ≥2-year postoperative PROMIS physical function, pain interference, pain intensity, and depression scores for 111 feet in 105 patients were included in the study. Significant postoperative improvement was defined using minimal clinically important differences (MCIDs). Logistic regression models and area under the curve (AUC) analyses were used to determine whether preoperative PROMIS scores were predictive of postoperative outcomes. Results: Receiver operating characteristic curves found statistically significant AUCs for the PROMIS physical function (AUC = 0.728, P = .004), pain intensity (AUC = 0.720, P = .018), and depression (AUC = 0.761, P < .001) domains. The preoperative PROMIS pain interference domain did not achieve a statistically significant AUC. Conclusion: Preoperative PROMIS physical function and pain intensity t scores may be used to predict postoperative improvement in patients following a fixed-bearing TAR; however, preoperative PROMIS pain interference scores were not good predictors. The results of this study may be used to guide research regarding patient-reported outcomes following TAR. Level of Evidence: Level III, retrospective comparative series.
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spelling doaj.art-bebb91f760954a73a7a63cf89fbd748e2022-12-21T18:56:09ZengSAGE PublishingFoot & Ankle Orthopaedics2473-01142021-07-01610.1177/24730114211020335Preoperative PROMIS Physical Function Scores Predict Postoperative Outcomes Following Total Ankle ReplacementMatthew S. Conti MD0Kristin C. Caolo BA1Agnes D. Cororaton MS2Jonathan T. Deland MD3Constantine A. Demetracopoulos MD4Scott J. Ellis MD5 Foot and Ankle Service, Hospital for Special Surgery, New York, NY, USA Foot and Ankle Service, Hospital for Special Surgery, New York, NY, USA Biostatistics Core, Hospital for Special Surgery, New York, NY, USA Foot and Ankle Service, Hospital for Special Surgery, New York, NY, USA Foot and Ankle Service, Hospital for Special Surgery, New York, NY, USA Foot and Ankle Service, Hospital for Special Surgery, New York, NY, USABackground: Despite good evidence that supports significant improvements in pain and physical function following a total ankle replacement (TAR) for end-stage ankle arthritis, there is a subset of patients who do not significantly benefit from surgery. The purpose of this study was to perform a preliminary analysis to determine if preoperative Patient-Reported Outcome Measurement Information System (PROMIS) scores could be used to predict which patients were at risk of not meaningfully improving following a TAR. Methods: Prospectively collected preoperative and ≥2-year postoperative PROMIS physical function, pain interference, pain intensity, and depression scores for 111 feet in 105 patients were included in the study. Significant postoperative improvement was defined using minimal clinically important differences (MCIDs). Logistic regression models and area under the curve (AUC) analyses were used to determine whether preoperative PROMIS scores were predictive of postoperative outcomes. Results: Receiver operating characteristic curves found statistically significant AUCs for the PROMIS physical function (AUC = 0.728, P = .004), pain intensity (AUC = 0.720, P = .018), and depression (AUC = 0.761, P < .001) domains. The preoperative PROMIS pain interference domain did not achieve a statistically significant AUC. Conclusion: Preoperative PROMIS physical function and pain intensity t scores may be used to predict postoperative improvement in patients following a fixed-bearing TAR; however, preoperative PROMIS pain interference scores were not good predictors. The results of this study may be used to guide research regarding patient-reported outcomes following TAR. Level of Evidence: Level III, retrospective comparative series.https://doi.org/10.1177/24730114211020335
spellingShingle Matthew S. Conti MD
Kristin C. Caolo BA
Agnes D. Cororaton MS
Jonathan T. Deland MD
Constantine A. Demetracopoulos MD
Scott J. Ellis MD
Preoperative PROMIS Physical Function Scores Predict Postoperative Outcomes Following Total Ankle Replacement
Foot & Ankle Orthopaedics
title Preoperative PROMIS Physical Function Scores Predict Postoperative Outcomes Following Total Ankle Replacement
title_full Preoperative PROMIS Physical Function Scores Predict Postoperative Outcomes Following Total Ankle Replacement
title_fullStr Preoperative PROMIS Physical Function Scores Predict Postoperative Outcomes Following Total Ankle Replacement
title_full_unstemmed Preoperative PROMIS Physical Function Scores Predict Postoperative Outcomes Following Total Ankle Replacement
title_short Preoperative PROMIS Physical Function Scores Predict Postoperative Outcomes Following Total Ankle Replacement
title_sort preoperative promis physical function scores predict postoperative outcomes following total ankle replacement
url https://doi.org/10.1177/24730114211020335
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