Autophagy linked FYVE (Alfy/WDFY3) is required for establishing neuronal connectivity in the mammalian brain

Autophagy linked FYVE (Alfy/WDFY3) is required for establishing neuronal connectivity in the mammalian brain

The regulation of protein degradation is essential for maintaining the appropriate environment to coordinate complex cell signaling events and to promote cellular remodeling. The Autophagy linked FYVE protein (Alfy), previously identified as a molecular scaffold between the ubiquitinated cargo and t...

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Bibliographic Details
Main Authors: Joanna M Dragich, Takaaki Kuwajima, Megumi Hirose-Ikeda, Michael S Yoon, Evelien Eenjes, Joan R Bosco, Leora M Fox, Alf H Lystad, Tinmarla F Oo, Olga Yarygina, Tomohiro Mita, Satoshi Waguri, Yoshinobu Ichimura, Masaaki Komatsu, Anne Simonsen, Robert E Burke, Carol A Mason, Ai Yamamoto
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-09-01
Series:eLife
Subjects:
Autophagy
Alfy
axon guidance
corpus callosum
neurodevelopment
Wdfy3
Online Access:https://elifesciences.org/articles/14810

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