Gender Differences in the Frequency of Positive and Negative Effects after Acute Caffeine Consumption

Gender-specific caffeine-related adverse effects should be thoroughly investigated. Sixty-five adult participants were included in the study, 30 men and 35 women (age, 22.5 ± 2.8; body weight, 71.7 ± 16.2 kg; BMI, 23.6 ± 4.4). The participants who were classified as low and moderate caffeine users r...

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Main Author: Przemysław Domaszewski
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Nutrients
Subjects:
Online Access:https://www.mdpi.com/2072-6643/15/6/1318
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author Przemysław Domaszewski
author_facet Przemysław Domaszewski
author_sort Przemysław Domaszewski
collection DOAJ
description Gender-specific caffeine-related adverse effects should be thoroughly investigated. Sixty-five adult participants were included in the study, 30 men and 35 women (age, 22.5 ± 2.8; body weight, 71.7 ± 16.2 kg; BMI, 23.6 ± 4.4). The participants who were classified as low and moderate caffeine users received 3 mg/kg, and high caffeine users received 6 mg/kg of caffeine in one dose. One hour after ingestion of caffeine and within twenty-four hours, the participants completed a side effect questionnaire. Effects after the ingestion of CAF were divided into two subgroups: negative (muscle soreness, increased urine output, tachycardia and palpitations, anxiety or nervousness, headache, gastrointestinal problems, and insomnia) and positive (perception improvement; increased vigor/activeness). Caffeine ingestion resulted in a statistically significant association between gender and negative effects one hour after ingestion (<i>p</i> = 0.049). Gender and positive effects one hour after ingestion (<i>p</i> = 0.005), and between gender and positive effects within 24 h after ingestion (<i>p</i> = 0.047). There were significant associations between gender and perception improvement (<i>p</i> = 0.032) and gender and increased vigor/activeness (<i>p</i> = 0.009) one hour after ingestion. Nearly 30% of men and 54% of women reported negative effects. At the same time, 20% of women and more than 50% of men reported positive effects. Gender is an important factor in the negative and positive effects of caffeine consumption.
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spelling doaj.art-bec5223f15b74b119a28547f2c19b6bb2023-11-17T13:04:04ZengMDPI AGNutrients2072-66432023-03-01156131810.3390/nu15061318Gender Differences in the Frequency of Positive and Negative Effects after Acute Caffeine ConsumptionPrzemysław Domaszewski0Department of Health Sciences, Institute of Health Sciences, University of Opole, 45-040 Opole, PolandGender-specific caffeine-related adverse effects should be thoroughly investigated. Sixty-five adult participants were included in the study, 30 men and 35 women (age, 22.5 ± 2.8; body weight, 71.7 ± 16.2 kg; BMI, 23.6 ± 4.4). The participants who were classified as low and moderate caffeine users received 3 mg/kg, and high caffeine users received 6 mg/kg of caffeine in one dose. One hour after ingestion of caffeine and within twenty-four hours, the participants completed a side effect questionnaire. Effects after the ingestion of CAF were divided into two subgroups: negative (muscle soreness, increased urine output, tachycardia and palpitations, anxiety or nervousness, headache, gastrointestinal problems, and insomnia) and positive (perception improvement; increased vigor/activeness). Caffeine ingestion resulted in a statistically significant association between gender and negative effects one hour after ingestion (<i>p</i> = 0.049). Gender and positive effects one hour after ingestion (<i>p</i> = 0.005), and between gender and positive effects within 24 h after ingestion (<i>p</i> = 0.047). There were significant associations between gender and perception improvement (<i>p</i> = 0.032) and gender and increased vigor/activeness (<i>p</i> = 0.009) one hour after ingestion. Nearly 30% of men and 54% of women reported negative effects. At the same time, 20% of women and more than 50% of men reported positive effects. Gender is an important factor in the negative and positive effects of caffeine consumption.https://www.mdpi.com/2072-6643/15/6/1318side effectspositive effectsgendercaffeineoptimalisation
spellingShingle Przemysław Domaszewski
Gender Differences in the Frequency of Positive and Negative Effects after Acute Caffeine Consumption
Nutrients
side effects
positive effects
gender
caffeine
optimalisation
title Gender Differences in the Frequency of Positive and Negative Effects after Acute Caffeine Consumption
title_full Gender Differences in the Frequency of Positive and Negative Effects after Acute Caffeine Consumption
title_fullStr Gender Differences in the Frequency of Positive and Negative Effects after Acute Caffeine Consumption
title_full_unstemmed Gender Differences in the Frequency of Positive and Negative Effects after Acute Caffeine Consumption
title_short Gender Differences in the Frequency of Positive and Negative Effects after Acute Caffeine Consumption
title_sort gender differences in the frequency of positive and negative effects after acute caffeine consumption
topic side effects
positive effects
gender
caffeine
optimalisation
url https://www.mdpi.com/2072-6643/15/6/1318
work_keys_str_mv AT przemysławdomaszewski genderdifferencesinthefrequencyofpositiveandnegativeeffectsafteracutecaffeineconsumption