Recurrent chromosomal copy number alterations in sporadic chordomas.

The molecular events in chordoma pathogenesis have not been fully delineated, particularly with respect to copy number changes. Understanding copy number alterations in chordoma may reveal critical disease mechanisms that could be exploited for tumor classification and therapy. We report the copy nu...

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Bibliographic Details
Main Authors: Long Phi Le, G Petur Nielsen, Andrew Eric Rosenberg, Dafydd Thomas, Julie M Batten, Vikram Deshpande, Joseph Schwab, Zhenfeng Duan, Ramnik J Xavier, Francis J Hornicek, A John Iafrate
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3094331?pdf=render