Selection of a Nuclease-Resistant RNA Aptamer Targeting CD19

Selection of a Nuclease-Resistant RNA Aptamer Targeting CD19

The transmembrane glycoprotein cluster of differentiation 19 (CD19) is a B cell–specific surface marker, expressed on the majority of neoplastic B cells, and has recently emerged as a very attractive biomarker and therapeutic target for B-cell malignancies. The development of safe and effective liga...

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Bibliographic Details
Main Authors: Carla L. Esposito, Katrien Van Roosbroeck, Gianluca Santamaria, Deborah Rotoli, Annamaria Sandomenico, William G. Wierda, Alessandra Ferrajoli, Menotti Ruvo, George A. Calin, Vittorio de Franciscis, Silvia Catuogno
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Cancers
Subjects:
CD19
aptamer
B-cells
cell-SELEX
Online Access:https://www.mdpi.com/2072-6694/13/20/5220

Internet

https://www.mdpi.com/2072-6694/13/20/5220

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