Systemic tryptophan homeostasis

Systemic tryptophan homeostasis

Tryptophan is an essential amino acid, which is not only a building block for protein synthesis, but also a precursor for the biosynthesis of co-enzymes and neuromodulators, such as NAD/NADP(H), kynurenic acid, melatonin and serotonin. It also plays a role in immune homeostasis, as local tryptophan...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser:	Simon Klaessens, Vincent Stroobant, Etienne De Plaen, Benoit J. Van den Eynde
Format:	Artikel
Sprache:	English
Veröffentlicht:	Frontiers Media S.A. 2022-09-01
Schriftenreihe:	Frontiers in Molecular Biosciences
Schlagworte:	tryptophan TDO (tryptophan 2,3-dioxygenase) IDO1 (indoleamine 2,3-dioxygenase 1) pellagra hartnup disease tumor
Online Zugang:	https://www.frontiersin.org/articles/10.3389/fmolb.2022.897929/full

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