Advances in near-infrared-activated lanthanide-doped optical nanomaterials: imaging, sensing, and therapy
As the population ages, cancer has become a major health concern. Although surgical treatment, chemoradiotherapy, and other clinical treatments have become dominant, their strong invasiveness and intolerable toxic side effects seriously affect patients' quality of life. Therefore, developing no...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-07-01
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| Series: | Materials & Design |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0264127523004513 |
| _version_ | 1797794102911172608 |
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| author | Hao Li Gongxun Bai Yanbang Lian Yinyan Li Liang Chen Junjie Zhang Shiqing Xu |
| author_facet | Hao Li Gongxun Bai Yanbang Lian Yinyan Li Liang Chen Junjie Zhang Shiqing Xu |
| author_sort | Hao Li |
| collection | DOAJ |
| description | As the population ages, cancer has become a major health concern. Although surgical treatment, chemoradiotherapy, and other clinical treatments have become dominant, their strong invasiveness and intolerable toxic side effects seriously affect patients' quality of life. Therefore, developing non-invasive optical therapy with high safety is of great significance. In the last two decades of development, great progress has been made in lanthanide doped nanoparticles on biomedical applications under near-infrared (NIR) light due to their unique properties. These nanomaterials have been used in a wide range of applications, including bioluminescence marker detection, in vitro and in vivo imaging, photodynamic therapy (PDT), photothermal therapy (PTT), and other therapeutic applications. These therapies have been rapidly developed in the profession involving oncology due to their non-invasive, spatiotemporal controllability, and high efficiency. For this key review, the applications based on lanthanide nanoparticles have been listed as follows: bioimaging, biosensors, PDT and PTT. Some emerging biological applications of lanthanide-doped nanoparticles currently at the forefront of the nano/biological interface are also discussed. Finally, this review summarizes the future opportunities and challenges of nanotechnology research based on lanthanide-doped nanoparticles. |
| first_indexed | 2024-03-13T02:56:53Z |
| format | Article |
| id | doaj.art-becc5184ad1440cabb24be14bbd5fca5 |
| institution | Directory Open Access Journal |
| issn | 0264-1275 |
| language | English |
| last_indexed | 2024-03-13T02:56:53Z |
| publishDate | 2023-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Materials & Design |
| spelling | doaj.art-becc5184ad1440cabb24be14bbd5fca52023-06-28T04:28:34ZengElsevierMaterials & Design0264-12752023-07-01231112036Advances in near-infrared-activated lanthanide-doped optical nanomaterials: imaging, sensing, and therapyHao Li0Gongxun Bai1Yanbang Lian2Yinyan Li3Liang Chen4Junjie Zhang5Shiqing Xu6Key Laboratory of Rare Earth Optoelectronic Materials and Devices of Zhejiang Province, College of Optical and Electronic Technology, China Jiliang University, Hangzhou 310018, ChinaKey Laboratory of Rare Earth Optoelectronic Materials and Devices of Zhejiang Province, College of Optical and Electronic Technology, China Jiliang University, Hangzhou 310018, China; Corresponding authors.Radiology Department, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, ChinaKey Laboratory of Rare Earth Optoelectronic Materials and Devices of Zhejiang Province, College of Optical and Electronic Technology, China Jiliang University, Hangzhou 310018, China; Corresponding authors.Key Laboratory of Rare Earth Optoelectronic Materials and Devices of Zhejiang Province, College of Optical and Electronic Technology, China Jiliang University, Hangzhou 310018, ChinaKey Laboratory of Rare Earth Optoelectronic Materials and Devices of Zhejiang Province, College of Optical and Electronic Technology, China Jiliang University, Hangzhou 310018, ChinaKey Laboratory of Rare Earth Optoelectronic Materials and Devices of Zhejiang Province, College of Optical and Electronic Technology, China Jiliang University, Hangzhou 310018, ChinaAs the population ages, cancer has become a major health concern. Although surgical treatment, chemoradiotherapy, and other clinical treatments have become dominant, their strong invasiveness and intolerable toxic side effects seriously affect patients' quality of life. Therefore, developing non-invasive optical therapy with high safety is of great significance. In the last two decades of development, great progress has been made in lanthanide doped nanoparticles on biomedical applications under near-infrared (NIR) light due to their unique properties. These nanomaterials have been used in a wide range of applications, including bioluminescence marker detection, in vitro and in vivo imaging, photodynamic therapy (PDT), photothermal therapy (PTT), and other therapeutic applications. These therapies have been rapidly developed in the profession involving oncology due to their non-invasive, spatiotemporal controllability, and high efficiency. For this key review, the applications based on lanthanide nanoparticles have been listed as follows: bioimaging, biosensors, PDT and PTT. Some emerging biological applications of lanthanide-doped nanoparticles currently at the forefront of the nano/biological interface are also discussed. Finally, this review summarizes the future opportunities and challenges of nanotechnology research based on lanthanide-doped nanoparticles.http://www.sciencedirect.com/science/article/pii/S0264127523004513NanomaterialsLanthanideLuminescent sensingPhotothermal therapyOptical imaging |
| spellingShingle | Hao Li Gongxun Bai Yanbang Lian Yinyan Li Liang Chen Junjie Zhang Shiqing Xu Advances in near-infrared-activated lanthanide-doped optical nanomaterials: imaging, sensing, and therapy Materials & Design Nanomaterials Lanthanide Luminescent sensing Photothermal therapy Optical imaging |
| title | Advances in near-infrared-activated lanthanide-doped optical nanomaterials: imaging, sensing, and therapy |
| title_full | Advances in near-infrared-activated lanthanide-doped optical nanomaterials: imaging, sensing, and therapy |
| title_fullStr | Advances in near-infrared-activated lanthanide-doped optical nanomaterials: imaging, sensing, and therapy |
| title_full_unstemmed | Advances in near-infrared-activated lanthanide-doped optical nanomaterials: imaging, sensing, and therapy |
| title_short | Advances in near-infrared-activated lanthanide-doped optical nanomaterials: imaging, sensing, and therapy |
| title_sort | advances in near infrared activated lanthanide doped optical nanomaterials imaging sensing and therapy |
| topic | Nanomaterials Lanthanide Luminescent sensing Photothermal therapy Optical imaging |
| url | http://www.sciencedirect.com/science/article/pii/S0264127523004513 |
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