Discovering the Triad between Nav1.5, Breast Cancer, and the Immune System: A Fundamental Review and Future Perspectives

Discovering the Triad between Nav1.5, Breast Cancer, and the Immune System: A Fundamental Review and Future Perspectives

Nav1.5 is one of the nine voltage-gated sodium channel-alpha subunit (VGSC-α) family members. The Nav1.5 channel typically carries an inward sodium ion current that depolarises the membrane potential during the upstroke of the cardiac action potential. The neonatal isoform of Nav1.5, nNav1.5, is pro...

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Bibliographic Details
Main Authors: Harishini Rajaratinam, Noor Fatmawati Mokhtar, Nurul Asma-Abdullah, Wan Ezumi Mohd Fuad
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Biomolecules
Subjects:
<i>SCN5A</i>
Nav1.5
neonatal Nav1.5
immune system
breast cancer
immunotherapy
Online Access:https://www.mdpi.com/2218-273X/12/2/310

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