Effects of apical sodium-bile acid transporter inhibitor and obeticholic acid co-treatment in experimental non-alcoholic steatohepatitis

Background and aims: Several bile acids-based monotherapies have been developed for non-alcoholic steatohepatitis (NASH) treatment but clinical trial findings suggest that they do not satisfactorily improve NASH and liver fibrosis in many patients. Recently, we have shown that combining a gut-restri...

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Bibliographic Details
Main Authors: David J. Matye, Xuan Qin, Mohammad Nazmul Hasan, Lijie Gu, Yung Dai Clayton, Feng Li, Tiangang Li
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2022-12-01
Series:Liver Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2542568422000617