Toward forward genetic screens in malaria-causing parasites using the piggyBac transposon
<p>Abstract</p> <p>The ability to analyze gene function in malaria-causing <it>Plasmodium </it>parasites has received a boost with a recent paper in <it>BMC Genomics </it>that describes a genome-wide mutagenesis system in the rodent malaria species <it>...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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BMC
2011-03-01
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| Series: | BMC Biology |
| Online Access: | http://www.biomedcentral.com/1741-7007/9/21 |
| Summary: | <p>Abstract</p> <p>The ability to analyze gene function in malaria-causing <it>Plasmodium </it>parasites has received a boost with a recent paper in <it>BMC Genomics </it>that describes a genome-wide mutagenesis system in the rodent malaria species <it>Plasmodium berghei </it>using the transposon <it>piggyBac</it>. This advance holds promise for identifying and validating new targets for intervention against malaria. But further improvements are still needed for the full power of genome-wide molecular genetic screens to be utilized in this organism.</p> <p>See research article: <url>http://www.biomedcentral.com/1471-2164/12/155</url></p> |
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| ISSN: | 1741-7007 |