Toward forward genetic screens in malaria-causing parasites using the piggyBac transposon
<p>Abstract</p> <p>The ability to analyze gene function in malaria-causing <it>Plasmodium </it>parasites has received a boost with a recent paper in <it>BMC Genomics </it>that describes a genome-wide mutagenesis system in the rodent malaria species <it>...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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BMC
2011-03-01
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| Series: | BMC Biology |
| Online Access: | http://www.biomedcentral.com/1741-7007/9/21 |
| _version_ | 1818264792394104832 |
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| author | de Koning-Ward Tania F Crabb Brendan S Gilson Paul R |
| author_facet | de Koning-Ward Tania F Crabb Brendan S Gilson Paul R |
| author_sort | de Koning-Ward Tania F |
| collection | DOAJ |
| description | <p>Abstract</p> <p>The ability to analyze gene function in malaria-causing <it>Plasmodium </it>parasites has received a boost with a recent paper in <it>BMC Genomics </it>that describes a genome-wide mutagenesis system in the rodent malaria species <it>Plasmodium berghei </it>using the transposon <it>piggyBac</it>. This advance holds promise for identifying and validating new targets for intervention against malaria. But further improvements are still needed for the full power of genome-wide molecular genetic screens to be utilized in this organism.</p> <p>See research article: <url>http://www.biomedcentral.com/1471-2164/12/155</url></p> |
| first_indexed | 2024-12-12T19:40:32Z |
| format | Article |
| id | doaj.art-beecfb59bd024ac7a29f507cb6c94832 |
| institution | Directory Open Access Journal |
| issn | 1741-7007 |
| language | English |
| last_indexed | 2024-12-12T19:40:32Z |
| publishDate | 2011-03-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Biology |
| spelling | doaj.art-beecfb59bd024ac7a29f507cb6c948322022-12-22T00:14:12ZengBMCBMC Biology1741-70072011-03-01912110.1186/1741-7007-9-21Toward forward genetic screens in malaria-causing parasites using the piggyBac transposonde Koning-Ward Tania FCrabb Brendan SGilson Paul R<p>Abstract</p> <p>The ability to analyze gene function in malaria-causing <it>Plasmodium </it>parasites has received a boost with a recent paper in <it>BMC Genomics </it>that describes a genome-wide mutagenesis system in the rodent malaria species <it>Plasmodium berghei </it>using the transposon <it>piggyBac</it>. This advance holds promise for identifying and validating new targets for intervention against malaria. But further improvements are still needed for the full power of genome-wide molecular genetic screens to be utilized in this organism.</p> <p>See research article: <url>http://www.biomedcentral.com/1471-2164/12/155</url></p>http://www.biomedcentral.com/1741-7007/9/21 |
| spellingShingle | de Koning-Ward Tania F Crabb Brendan S Gilson Paul R Toward forward genetic screens in malaria-causing parasites using the piggyBac transposon BMC Biology |
| title | Toward forward genetic screens in malaria-causing parasites using the piggyBac transposon |
| title_full | Toward forward genetic screens in malaria-causing parasites using the piggyBac transposon |
| title_fullStr | Toward forward genetic screens in malaria-causing parasites using the piggyBac transposon |
| title_full_unstemmed | Toward forward genetic screens in malaria-causing parasites using the piggyBac transposon |
| title_short | Toward forward genetic screens in malaria-causing parasites using the piggyBac transposon |
| title_sort | toward forward genetic screens in malaria causing parasites using the piggybac transposon |
| url | http://www.biomedcentral.com/1741-7007/9/21 |
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