Comparing the Scores of Sequential Organ Failure Assessment and a Proposed Bedside Tool in Patients with Systemic Inflammatory Response Syndrome Admitted to ICU
Background and purpose: Sequential organ failure assessment (SOFA) is used to assess the severity of the disease and mortality rate in patients admitted to ICU. SOFA requires experiments that are impractical in centers with limited resources. The aim of this study was to compare the diagnostic value...
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| Format: | Article |
| Language: | English |
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Mazandaran University of Medical Sciences
2022-01-01
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| Series: | Journal of Mazandaran University of Medical Sciences |
| Subjects: | |
| Online Access: | http://jmums.mazums.ac.ir/article-1-16175-en.html |
| _version_ | 1828003398478200832 |
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| author | Afshin Gholipour Baradari Fateme Heydari Abbas Alipour Anahita Babaei |
| author_facet | Afshin Gholipour Baradari Fateme Heydari Abbas Alipour Anahita Babaei |
| author_sort | Afshin Gholipour Baradari |
| collection | DOAJ |
| description | Background and purpose: Sequential organ failure assessment (SOFA) is used to assess the severity of the disease and mortality rate in patients admitted to ICU. SOFA requires experiments that are impractical in centers with limited resources. The aim of this study was to compare the diagnostic value of bedside SOFA (b SOFA) and SOFA scores in mortality of ICU patients.
Materials and methods: This cohort study was performed in 60 patients with Systemic Inflammatory Response Syndrome (SIRS) older than 18 years of age. SOFA and b SOFA scores were recorded at admission, then daily until admission at ICU.
Results: According to the Lin and Bland-Altman agreement coefficient, there was a very good agreement between SOFA and b SOFA scores at days 1, 15, 16, 17, 18, and 20. At days 3, 5, 7, 14, and 19 we observed a good agreement and significant correlation between SOFA and b SOFA scores. Findings showed a moderate agreement between SOFA and b SOFA scores at days 2, 4, 6, 8, 9, 10, 11, 12, and 13, but at days 13 and 15 there was a direct relationship between the two scores (P>0.05). Area Under Curve (AUC) method in ROC Curve showed no significant difference in diagnostic value between SOFA and b SOFA scores except at day 17 (P>0.05), indicating acceptable diagnostic value of b SOFA score compared to SOFA score. The sensitivity and specificity of the tools in terms of prognosis were found to be very close at different times showing similar diagnostic values.
Conclusion: The study showed diagnostic accuracy, and high sensitivity and specificity for predicting mortality and strong positive correlation between the two tools, so b SOFA is a suitable alternative due to lower cost with greater ease. |
| first_indexed | 2024-04-10T06:57:31Z |
| format | Article |
| id | doaj.art-bef026b1eed24c82b923a4428e5ec145 |
| institution | Directory Open Access Journal |
| issn | 1735-9260 1735-9279 |
| language | English |
| last_indexed | 2024-04-10T06:57:31Z |
| publishDate | 2022-01-01 |
| publisher | Mazandaran University of Medical Sciences |
| record_format | Article |
| series | Journal of Mazandaran University of Medical Sciences |
| spelling | doaj.art-bef026b1eed24c82b923a4428e5ec1452023-02-28T06:41:33ZengMazandaran University of Medical SciencesJournal of Mazandaran University of Medical Sciences1735-92601735-92792022-01-01312046272Comparing the Scores of Sequential Organ Failure Assessment and a Proposed Bedside Tool in Patients with Systemic Inflammatory Response Syndrome Admitted to ICUAfshin Gholipour Baradari0Fateme Heydari1Abbas Alipour2Anahita Babaei3 Professor, Department of Anesthesiology, Diabetes Research Center and Orthopedic Research Center, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran Assistant Professor, Department of Anesthesiology , Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran Associate Professor, Department of Community Medicine, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran ICU Resident, Department of Anesthesiology, Mazandaran University of Medical Sciences, Sari, Iran Background and purpose: Sequential organ failure assessment (SOFA) is used to assess the severity of the disease and mortality rate in patients admitted to ICU. SOFA requires experiments that are impractical in centers with limited resources. The aim of this study was to compare the diagnostic value of bedside SOFA (b SOFA) and SOFA scores in mortality of ICU patients. Materials and methods: This cohort study was performed in 60 patients with Systemic Inflammatory Response Syndrome (SIRS) older than 18 years of age. SOFA and b SOFA scores were recorded at admission, then daily until admission at ICU. Results: According to the Lin and Bland-Altman agreement coefficient, there was a very good agreement between SOFA and b SOFA scores at days 1, 15, 16, 17, 18, and 20. At days 3, 5, 7, 14, and 19 we observed a good agreement and significant correlation between SOFA and b SOFA scores. Findings showed a moderate agreement between SOFA and b SOFA scores at days 2, 4, 6, 8, 9, 10, 11, 12, and 13, but at days 13 and 15 there was a direct relationship between the two scores (P>0.05). Area Under Curve (AUC) method in ROC Curve showed no significant difference in diagnostic value between SOFA and b SOFA scores except at day 17 (P>0.05), indicating acceptable diagnostic value of b SOFA score compared to SOFA score. The sensitivity and specificity of the tools in terms of prognosis were found to be very close at different times showing similar diagnostic values. Conclusion: The study showed diagnostic accuracy, and high sensitivity and specificity for predicting mortality and strong positive correlation between the two tools, so b SOFA is a suitable alternative due to lower cost with greater ease.http://jmums.mazums.ac.ir/article-1-16175-en.htmlsequential organ failure assessmentsystemic inflammatory response syndromemulti organ failure |
| spellingShingle | Afshin Gholipour Baradari Fateme Heydari Abbas Alipour Anahita Babaei Comparing the Scores of Sequential Organ Failure Assessment and a Proposed Bedside Tool in Patients with Systemic Inflammatory Response Syndrome Admitted to ICU Journal of Mazandaran University of Medical Sciences sequential organ failure assessment systemic inflammatory response syndrome multi organ failure |
| title | Comparing the Scores of Sequential Organ Failure Assessment and a Proposed Bedside Tool in Patients with Systemic Inflammatory Response Syndrome Admitted to ICU |
| title_full | Comparing the Scores of Sequential Organ Failure Assessment and a Proposed Bedside Tool in Patients with Systemic Inflammatory Response Syndrome Admitted to ICU |
| title_fullStr | Comparing the Scores of Sequential Organ Failure Assessment and a Proposed Bedside Tool in Patients with Systemic Inflammatory Response Syndrome Admitted to ICU |
| title_full_unstemmed | Comparing the Scores of Sequential Organ Failure Assessment and a Proposed Bedside Tool in Patients with Systemic Inflammatory Response Syndrome Admitted to ICU |
| title_short | Comparing the Scores of Sequential Organ Failure Assessment and a Proposed Bedside Tool in Patients with Systemic Inflammatory Response Syndrome Admitted to ICU |
| title_sort | comparing the scores of sequential organ failure assessment and a proposed bedside tool in patients with systemic inflammatory response syndrome admitted to icu |
| topic | sequential organ failure assessment systemic inflammatory response syndrome multi organ failure |
| url | http://jmums.mazums.ac.ir/article-1-16175-en.html |
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