Prevalence and risk factors of type II endoleaks after endovascular aneurysm repair: A meta-analysis.

OBJECTIVES:This systematic review and meta-analysis aims to determine the current evidence on risk factors for type II endoleaks after endovascular aneurysm repair (EVAR). MATERIALS AND METHODS:A systematic literature search was carried out for studies that evaluated the association of demographic,...

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Main Authors: Qiang Guo, Xiaojiong Du, Jichun Zhao, Yukui Ma, Bin Huang, Ding Yuan, Yi Yang, Guojun Zeng, Fei Xiong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5300210?pdf=render
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author Qiang Guo
Xiaojiong Du
Jichun Zhao
Yukui Ma
Bin Huang
Ding Yuan
Yi Yang
Guojun Zeng
Fei Xiong
author_facet Qiang Guo
Xiaojiong Du
Jichun Zhao
Yukui Ma
Bin Huang
Ding Yuan
Yi Yang
Guojun Zeng
Fei Xiong
author_sort Qiang Guo
collection DOAJ
description OBJECTIVES:This systematic review and meta-analysis aims to determine the current evidence on risk factors for type II endoleaks after endovascular aneurysm repair (EVAR). MATERIALS AND METHODS:A systematic literature search was carried out for studies that evaluated the association of demographic, co-morbidity, and other patient-determined factors with the onset of type II endoleaks. Pooled prevalence of type II endoleaks after EVAR was updated. RESULTS:Among the 504 studies screened, 45 studies with a total of 36,588 participants were included in this review. The pooled prevalence of type II endoleaks after EVAR was 22% [95% confidence interval (CI), 19%-25%]. The main factors consistently associated with type II endoleaks included age [pooled odds ratio (OR), 0.37; 95% CI, 0.31-0.43; P<0.001], smoking (pooled OR, 0.71; 95% CI, 0.55-0.92; P<0.001), patent inferior mesenteric artery (pooled OR, 1.98; 95% CI, 1.06-3.71; P = 0.012), maximum aneurysm diameter (pooled OR, 0.23; 95% CI, 0.17-0.30; P<0.001), and number of patent lumbar arteries (pooled OR, 3.07; 95% CI, 2.81-3.33; P<0.001). Sex, diabetes, hypertension, anticoagulants, antiplatelet, hyperlipidemia, chronic renal insufficiency, types of graft material, and chronic obstructive pulmonary diseases (COPD) did not show any association with the onset of type II endoleaks. CONCLUSIONS:Clinicians can use the identified risk factors to detect and manage patients at risk of developing type II endoleaks after EVAR. However, further studies are needed to analyze a number of potential risk factors.
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spelling doaj.art-bef068efa2174b2ab5fd9c7cb86d18e02022-12-22T00:04:31ZengPublic Library of Science (PLoS)PLoS ONE1932-62032017-01-01122e017060010.1371/journal.pone.0170600Prevalence and risk factors of type II endoleaks after endovascular aneurysm repair: A meta-analysis.Qiang GuoXiaojiong DuJichun ZhaoYukui MaBin HuangDing YuanYi YangGuojun ZengFei XiongOBJECTIVES:This systematic review and meta-analysis aims to determine the current evidence on risk factors for type II endoleaks after endovascular aneurysm repair (EVAR). MATERIALS AND METHODS:A systematic literature search was carried out for studies that evaluated the association of demographic, co-morbidity, and other patient-determined factors with the onset of type II endoleaks. Pooled prevalence of type II endoleaks after EVAR was updated. RESULTS:Among the 504 studies screened, 45 studies with a total of 36,588 participants were included in this review. The pooled prevalence of type II endoleaks after EVAR was 22% [95% confidence interval (CI), 19%-25%]. The main factors consistently associated with type II endoleaks included age [pooled odds ratio (OR), 0.37; 95% CI, 0.31-0.43; P<0.001], smoking (pooled OR, 0.71; 95% CI, 0.55-0.92; P<0.001), patent inferior mesenteric artery (pooled OR, 1.98; 95% CI, 1.06-3.71; P = 0.012), maximum aneurysm diameter (pooled OR, 0.23; 95% CI, 0.17-0.30; P<0.001), and number of patent lumbar arteries (pooled OR, 3.07; 95% CI, 2.81-3.33; P<0.001). Sex, diabetes, hypertension, anticoagulants, antiplatelet, hyperlipidemia, chronic renal insufficiency, types of graft material, and chronic obstructive pulmonary diseases (COPD) did not show any association with the onset of type II endoleaks. CONCLUSIONS:Clinicians can use the identified risk factors to detect and manage patients at risk of developing type II endoleaks after EVAR. However, further studies are needed to analyze a number of potential risk factors.http://europepmc.org/articles/PMC5300210?pdf=render
spellingShingle Qiang Guo
Xiaojiong Du
Jichun Zhao
Yukui Ma
Bin Huang
Ding Yuan
Yi Yang
Guojun Zeng
Fei Xiong
Prevalence and risk factors of type II endoleaks after endovascular aneurysm repair: A meta-analysis.
PLoS ONE
title Prevalence and risk factors of type II endoleaks after endovascular aneurysm repair: A meta-analysis.
title_full Prevalence and risk factors of type II endoleaks after endovascular aneurysm repair: A meta-analysis.
title_fullStr Prevalence and risk factors of type II endoleaks after endovascular aneurysm repair: A meta-analysis.
title_full_unstemmed Prevalence and risk factors of type II endoleaks after endovascular aneurysm repair: A meta-analysis.
title_short Prevalence and risk factors of type II endoleaks after endovascular aneurysm repair: A meta-analysis.
title_sort prevalence and risk factors of type ii endoleaks after endovascular aneurysm repair a meta analysis
url http://europepmc.org/articles/PMC5300210?pdf=render
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