Kidney damage in burn disease. Part 1. Pathomorphophysiology (literature review)

Acute kidney injury (AKI) is a common complication in critically ill burn patients and is associated with serious adverse outcomes, including increased length of hospital stay, development of chronic kidney disease, and increased risk of mortality. The incidence of AKI among burn patients in the int...

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Main Authors: O.V. Kravets, V.V. Yekhalov, V.V. Gorbuntsov, D.A. Krishtafor
Format: Article
Language:English
Published: Zaslavsky O.Yu. 2023-12-01
Series:Počki
Subjects:
Online Access:https://kidneys.zaslavsky.com.ua/index.php/journal/article/view/430
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author O.V. Kravets
V.V. Yekhalov
V.V. Gorbuntsov
D.A. Krishtafor
author_facet O.V. Kravets
V.V. Yekhalov
V.V. Gorbuntsov
D.A. Krishtafor
author_sort O.V. Kravets
collection DOAJ
description Acute kidney injury (AKI) is a common complication in critically ill burn patients and is associated with serious adverse outcomes, including increased length of hospital stay, development of chronic kidney disease, and increased risk of mortality. The incidence of AKI among burn patients in the intensive care units is 38 (30–46) %. A high percentage of the total burn surface area and a number of individual predisposing factors are considered to be the leading risk factors for AKI. Pathophysiological and morphological changes in the body under the combination of burn disease and kidney damage have certain discrepancies with the classical course of the pathological process in some nosological forms. Despite significant progress in the technologies of fluid resuscitation, intensive care and renal replacement therapy in recent years, the morbidity and mortality rate in such patients remain quite significant. A better understanding of clinical characteristics, early detection and prevention of risk factors for kidney damage in burns, as well as timely medical intervention can effectively reduce morbidity and progression of the pathological process, and also optimize the prognosis in the long run.
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spelling doaj.art-bef2512802e644fe9d17b705d41184542024-01-30T07:12:42ZengZaslavsky O.Yu.Počki2307-12572307-12652023-12-0112420321010.22141/2307-1257.12.4.2023.430430Kidney damage in burn disease. Part 1. Pathomorphophysiology (literature review)O.V. Kravets0https://orcid.org/0000-0003-1340-3290V.V. Yekhalov1https://orcid.org/0000-0001-5373-3820V.V. Gorbuntsov2https://orcid.org/0000-0001-7752-0993D.A. Krishtafor3https://orcid.org/0000-0003-0942-4099Dnipro State Medical University, Dnipro, UkraineDnipro State Medical University, Dnipro, UkraineDnipro State Medical University, Dnipro, UkraineDnipro State Medical University, Dnipro, UkraineAcute kidney injury (AKI) is a common complication in critically ill burn patients and is associated with serious adverse outcomes, including increased length of hospital stay, development of chronic kidney disease, and increased risk of mortality. The incidence of AKI among burn patients in the intensive care units is 38 (30–46) %. A high percentage of the total burn surface area and a number of individual predisposing factors are considered to be the leading risk factors for AKI. Pathophysiological and morphological changes in the body under the combination of burn disease and kidney damage have certain discrepancies with the classical course of the pathological process in some nosological forms. Despite significant progress in the technologies of fluid resuscitation, intensive care and renal replacement therapy in recent years, the morbidity and mortality rate in such patients remain quite significant. A better understanding of clinical characteristics, early detection and prevention of risk factors for kidney damage in burns, as well as timely medical intervention can effectively reduce morbidity and progression of the pathological process, and also optimize the prognosis in the long run.https://kidneys.zaslavsky.com.ua/index.php/journal/article/view/430reviewacute kidney injuryburn diseasechronic kidney diseasepathomorphologypathophysiology
spellingShingle O.V. Kravets
V.V. Yekhalov
V.V. Gorbuntsov
D.A. Krishtafor
Kidney damage in burn disease. Part 1. Pathomorphophysiology (literature review)
Počki
review
acute kidney injury
burn disease
chronic kidney disease
pathomorphology
pathophysiology
title Kidney damage in burn disease. Part 1. Pathomorphophysiology (literature review)
title_full Kidney damage in burn disease. Part 1. Pathomorphophysiology (literature review)
title_fullStr Kidney damage in burn disease. Part 1. Pathomorphophysiology (literature review)
title_full_unstemmed Kidney damage in burn disease. Part 1. Pathomorphophysiology (literature review)
title_short Kidney damage in burn disease. Part 1. Pathomorphophysiology (literature review)
title_sort kidney damage in burn disease part 1 pathomorphophysiology literature review
topic review
acute kidney injury
burn disease
chronic kidney disease
pathomorphology
pathophysiology
url https://kidneys.zaslavsky.com.ua/index.php/journal/article/view/430
work_keys_str_mv AT ovkravets kidneydamageinburndiseasepart1pathomorphophysiologyliteraturereview
AT vvyekhalov kidneydamageinburndiseasepart1pathomorphophysiologyliteraturereview
AT vvgorbuntsov kidneydamageinburndiseasepart1pathomorphophysiologyliteraturereview
AT dakrishtafor kidneydamageinburndiseasepart1pathomorphophysiologyliteraturereview