Kidney damage in burn disease. Part 1. Pathomorphophysiology (literature review)
Acute kidney injury (AKI) is a common complication in critically ill burn patients and is associated with serious adverse outcomes, including increased length of hospital stay, development of chronic kidney disease, and increased risk of mortality. The incidence of AKI among burn patients in the int...
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Format: | Article |
Language: | English |
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Zaslavsky O.Yu.
2023-12-01
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Series: | Počki |
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Online Access: | https://kidneys.zaslavsky.com.ua/index.php/journal/article/view/430 |
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author | O.V. Kravets V.V. Yekhalov V.V. Gorbuntsov D.A. Krishtafor |
author_facet | O.V. Kravets V.V. Yekhalov V.V. Gorbuntsov D.A. Krishtafor |
author_sort | O.V. Kravets |
collection | DOAJ |
description | Acute kidney injury (AKI) is a common complication in critically ill burn patients and is associated with serious adverse outcomes, including increased length of hospital stay, development of chronic kidney disease, and increased risk of mortality. The incidence of AKI among burn patients in the intensive care units is 38 (30–46) %. A high percentage of the total burn surface area and a number of individual predisposing factors are considered to be the leading risk factors for AKI. Pathophysiological and morphological changes in the body under the combination of burn disease and kidney damage have certain discrepancies with the classical course of the pathological process in some nosological forms. Despite significant progress in the technologies of fluid resuscitation, intensive care and renal replacement therapy in recent years, the morbidity and mortality rate in such patients remain quite significant. A better understanding of clinical characteristics, early detection and prevention of risk factors for kidney damage in burns, as well as timely medical intervention can effectively reduce morbidity and progression of the pathological process, and also optimize the prognosis in the long run. |
first_indexed | 2024-03-08T09:38:11Z |
format | Article |
id | doaj.art-bef2512802e644fe9d17b705d4118454 |
institution | Directory Open Access Journal |
issn | 2307-1257 2307-1265 |
language | English |
last_indexed | 2024-03-08T09:38:11Z |
publishDate | 2023-12-01 |
publisher | Zaslavsky O.Yu. |
record_format | Article |
series | Počki |
spelling | doaj.art-bef2512802e644fe9d17b705d41184542024-01-30T07:12:42ZengZaslavsky O.Yu.Počki2307-12572307-12652023-12-0112420321010.22141/2307-1257.12.4.2023.430430Kidney damage in burn disease. Part 1. Pathomorphophysiology (literature review)O.V. Kravets0https://orcid.org/0000-0003-1340-3290V.V. Yekhalov1https://orcid.org/0000-0001-5373-3820V.V. Gorbuntsov2https://orcid.org/0000-0001-7752-0993D.A. Krishtafor3https://orcid.org/0000-0003-0942-4099Dnipro State Medical University, Dnipro, UkraineDnipro State Medical University, Dnipro, UkraineDnipro State Medical University, Dnipro, UkraineDnipro State Medical University, Dnipro, UkraineAcute kidney injury (AKI) is a common complication in critically ill burn patients and is associated with serious adverse outcomes, including increased length of hospital stay, development of chronic kidney disease, and increased risk of mortality. The incidence of AKI among burn patients in the intensive care units is 38 (30–46) %. A high percentage of the total burn surface area and a number of individual predisposing factors are considered to be the leading risk factors for AKI. Pathophysiological and morphological changes in the body under the combination of burn disease and kidney damage have certain discrepancies with the classical course of the pathological process in some nosological forms. Despite significant progress in the technologies of fluid resuscitation, intensive care and renal replacement therapy in recent years, the morbidity and mortality rate in such patients remain quite significant. A better understanding of clinical characteristics, early detection and prevention of risk factors for kidney damage in burns, as well as timely medical intervention can effectively reduce morbidity and progression of the pathological process, and also optimize the prognosis in the long run.https://kidneys.zaslavsky.com.ua/index.php/journal/article/view/430reviewacute kidney injuryburn diseasechronic kidney diseasepathomorphologypathophysiology |
spellingShingle | O.V. Kravets V.V. Yekhalov V.V. Gorbuntsov D.A. Krishtafor Kidney damage in burn disease. Part 1. Pathomorphophysiology (literature review) Počki review acute kidney injury burn disease chronic kidney disease pathomorphology pathophysiology |
title | Kidney damage in burn disease. Part 1. Pathomorphophysiology (literature review) |
title_full | Kidney damage in burn disease. Part 1. Pathomorphophysiology (literature review) |
title_fullStr | Kidney damage in burn disease. Part 1. Pathomorphophysiology (literature review) |
title_full_unstemmed | Kidney damage in burn disease. Part 1. Pathomorphophysiology (literature review) |
title_short | Kidney damage in burn disease. Part 1. Pathomorphophysiology (literature review) |
title_sort | kidney damage in burn disease part 1 pathomorphophysiology literature review |
topic | review acute kidney injury burn disease chronic kidney disease pathomorphology pathophysiology |
url | https://kidneys.zaslavsky.com.ua/index.php/journal/article/view/430 |
work_keys_str_mv | AT ovkravets kidneydamageinburndiseasepart1pathomorphophysiologyliteraturereview AT vvyekhalov kidneydamageinburndiseasepart1pathomorphophysiologyliteraturereview AT vvgorbuntsov kidneydamageinburndiseasepart1pathomorphophysiologyliteraturereview AT dakrishtafor kidneydamageinburndiseasepart1pathomorphophysiologyliteraturereview |