Intrapulmonary Bronchogenic Cysts: Computed Tomography, Clinical and Histopathologic Correlations
Bronchogenic cysts (BCs) are usually located in the mediastinum and they occur less commonly in the lung parenchyma. This study investigated the findings from computed tomography (CT) images, clinical presentation and histopathologic findings of intrapulmonary BCs. Methods: From the last 7 years, th...
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| Format: | Article |
| Language: | English |
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Elsevier
2007-01-01
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| Series: | Journal of the Formosan Medical Association |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0929664609602102 |
| _version_ | 1818487927806623744 |
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| author | Yeun-Chung Chang Yih-Leong Chang Ssu-Yuan Chen Teh-Chen Wang Pan-Chyr Yang Hon-Man Liu Yung-Chie Lee |
| author_facet | Yeun-Chung Chang Yih-Leong Chang Ssu-Yuan Chen Teh-Chen Wang Pan-Chyr Yang Hon-Man Liu Yung-Chie Lee |
| author_sort | Yeun-Chung Chang |
| collection | DOAJ |
| description | Bronchogenic cysts (BCs) are usually located in the mediastinum and they occur less commonly in the lung parenchyma. This study investigated the findings from computed tomography (CT) images, clinical presentation and histopathologic findings of intrapulmonary BCs.
Methods: From the last 7 years, the CT images of 20 patients (12 females, 8 males; mean age, 38.8 ± 21.7 year; median age, 34 years) with intrapulmonary BC were available. Contrast-enhanced CT findings were characterized and correlated with clinical presentation and histopathologic findings (using Fisher's exact tests).
Results: The majority of intrapulmonary BCs were subpleural in location (55%), in the lower lobes (60%), symptomatic (80%), and in adults (90%). Three CT patterns were identified: cyst with content of fluid attenuation (9 patients), cyst with air and fluid content (9 patients), cyst with content of soft tissue attenuation (2 patients). Preoperative diagnosis of intrapulmonary BC was correct in only 20% using the CT criteria of cysts with fluid attenuation and without anomalous blood supply. Cysts with air component were significantly larger than those without air component (p = 0.0452), but cyst size and air component were not correlated with clinical presentation. Surrounding infiltration or thick wall on CT were significantly correlated with the presence of any clinical symptom (p = 0.014) or fever (p = 0.042). CT findings of surrounding consolidation, ground glass opacity or thick wall were significantly correlated with chronic inflammation or pneumonic change on histopathology (p = 0.0008).
Conclusion: There is a wide spectrum of intrapulmonary BCs that have CT findings that are correlated with clinical presentations and histopathologic findings. [J Formos Med Assoc 2007;106(1):8-15] |
| first_indexed | 2024-12-10T16:44:40Z |
| format | Article |
| id | doaj.art-bef3c6e607ca4af3b68812b71ec6cac9 |
| institution | Directory Open Access Journal |
| issn | 0929-6646 |
| language | English |
| last_indexed | 2024-12-10T16:44:40Z |
| publishDate | 2007-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of the Formosan Medical Association |
| spelling | doaj.art-bef3c6e607ca4af3b68812b71ec6cac92022-12-22T01:41:07ZengElsevierJournal of the Formosan Medical Association0929-66462007-01-01106181510.1016/S0929-6646(09)60210-2Intrapulmonary Bronchogenic Cysts: Computed Tomography, Clinical and Histopathologic CorrelationsYeun-Chung Chang0Yih-Leong Chang1Ssu-Yuan Chen2Teh-Chen Wang3Pan-Chyr Yang4Hon-Man Liu5Yung-Chie Lee6Department of Medical Imaging, Taipei, TaiwanDepartment of Pathology, Taipei, TaiwanDepartments of Physical Medicine and Rehabilitation, Taipei, TaiwanDepartment of Internal Medicine, Taipei, TaiwanDepartments of Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, TaiwanDepartment of Medical Imaging, Taipei, TaiwanDepartment of Radiology, Taipei City Hospital Yang-Ming Branch, Taipei, TaiwanBronchogenic cysts (BCs) are usually located in the mediastinum and they occur less commonly in the lung parenchyma. This study investigated the findings from computed tomography (CT) images, clinical presentation and histopathologic findings of intrapulmonary BCs. Methods: From the last 7 years, the CT images of 20 patients (12 females, 8 males; mean age, 38.8 ± 21.7 year; median age, 34 years) with intrapulmonary BC were available. Contrast-enhanced CT findings were characterized and correlated with clinical presentation and histopathologic findings (using Fisher's exact tests). Results: The majority of intrapulmonary BCs were subpleural in location (55%), in the lower lobes (60%), symptomatic (80%), and in adults (90%). Three CT patterns were identified: cyst with content of fluid attenuation (9 patients), cyst with air and fluid content (9 patients), cyst with content of soft tissue attenuation (2 patients). Preoperative diagnosis of intrapulmonary BC was correct in only 20% using the CT criteria of cysts with fluid attenuation and without anomalous blood supply. Cysts with air component were significantly larger than those without air component (p = 0.0452), but cyst size and air component were not correlated with clinical presentation. Surrounding infiltration or thick wall on CT were significantly correlated with the presence of any clinical symptom (p = 0.014) or fever (p = 0.042). CT findings of surrounding consolidation, ground glass opacity or thick wall were significantly correlated with chronic inflammation or pneumonic change on histopathology (p = 0.0008). Conclusion: There is a wide spectrum of intrapulmonary BCs that have CT findings that are correlated with clinical presentations and histopathologic findings. [J Formos Med Assoc 2007;106(1):8-15]http://www.sciencedirect.com/science/article/pii/S0929664609602102bronchiclinicopathologic featurescomputed tomographycystlung |
| spellingShingle | Yeun-Chung Chang Yih-Leong Chang Ssu-Yuan Chen Teh-Chen Wang Pan-Chyr Yang Hon-Man Liu Yung-Chie Lee Intrapulmonary Bronchogenic Cysts: Computed Tomography, Clinical and Histopathologic Correlations Journal of the Formosan Medical Association bronchi clinicopathologic features computed tomography cyst lung |
| title | Intrapulmonary Bronchogenic Cysts: Computed Tomography, Clinical and Histopathologic Correlations |
| title_full | Intrapulmonary Bronchogenic Cysts: Computed Tomography, Clinical and Histopathologic Correlations |
| title_fullStr | Intrapulmonary Bronchogenic Cysts: Computed Tomography, Clinical and Histopathologic Correlations |
| title_full_unstemmed | Intrapulmonary Bronchogenic Cysts: Computed Tomography, Clinical and Histopathologic Correlations |
| title_short | Intrapulmonary Bronchogenic Cysts: Computed Tomography, Clinical and Histopathologic Correlations |
| title_sort | intrapulmonary bronchogenic cysts computed tomography clinical and histopathologic correlations |
| topic | bronchi clinicopathologic features computed tomography cyst lung |
| url | http://www.sciencedirect.com/science/article/pii/S0929664609602102 |
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