Simultaneous Screening of 322 Residual Pesticides in Fruits and Vegetables Using GC-MS/MS and Deterministic Health Risk Assessments
The development of efficient methods for evaluating pesticide residues is essential in order to ensure the safety and quality of agricultural products since the Republic of Korea implemented the Positive List System (PLS). The objective of this research was to establish a method for the simultaneous...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-08-01
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| Series: | Foods |
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| Online Access: | https://www.mdpi.com/2304-8158/12/16/3001 |
| _version_ | 1797584786460508160 |
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| author | Byong-Sun Choi Dong-Uk Lee Woo-Seong Kim Chan-Woong Park Won-Jo Choe Myung-Jun Moon |
| author_facet | Byong-Sun Choi Dong-Uk Lee Woo-Seong Kim Chan-Woong Park Won-Jo Choe Myung-Jun Moon |
| author_sort | Byong-Sun Choi |
| collection | DOAJ |
| description | The development of efficient methods for evaluating pesticide residues is essential in order to ensure the safety and quality of agricultural products since the Republic of Korea implemented the Positive List System (PLS). The objective of this research was to establish a method for the simultaneous analysis of 322 pesticide residues in fruits and vegetables (such as coffee, potato, corn, and chili pepper), using the quick, easy, cheap, effective, rugged, and safe (QuEChERS) approach in combination with gas chromatography-tandem mass spectrometry (GC-MS/MS). This study introduces a robust, high-throughput GC-MS/MS method for screening the target pesticide residues in agricultural products, achieving the PLS criterion of 0.01 mg/kg LOQ. Despite some compounds not aligning with the CODEX recovery guideline, sufficient reproducibility was confirmed, attesting to the method’s applicability in qualitative analyses. A health risk assessment conducted using estimated daily intake/acceptable daily intake ratios indicated low risks associated with product consumption (<0.035391%), thereby confirming their safety. This efficient method holds significant implications for the safe distribution of agricultural products, including during import inspections. |
| first_indexed | 2024-03-10T23:57:38Z |
| format | Article |
| id | doaj.art-bef8d65880424b7189a406f3854f6b1e |
| institution | Directory Open Access Journal |
| issn | 2304-8158 |
| language | English |
| last_indexed | 2024-03-10T23:57:38Z |
| publishDate | 2023-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Foods |
| spelling | doaj.art-bef8d65880424b7189a406f3854f6b1e2023-11-19T01:05:12ZengMDPI AGFoods2304-81582023-08-011216300110.3390/foods12163001Simultaneous Screening of 322 Residual Pesticides in Fruits and Vegetables Using GC-MS/MS and Deterministic Health Risk AssessmentsByong-Sun Choi0Dong-Uk Lee1Woo-Seong Kim2Chan-Woong Park3Won-Jo Choe4Myung-Jun Moon5Department of Industrial Chemistry, Pukyong National University, Busan 48513, Republic of KoreaBiomedical Manufacturing Technology Center, Korea Institute of Industrial Technology, Yeongcheon 38822, Republic of KoreaCenter of Food & Drug Analysis, Busan Regional Office of Food and Drug Safety, Ministry of Food and Drug Safety, Busan 47537, Republic of KoreaCenter of Food & Drug Analysis, Busan Regional Office of Food and Drug Safety, Ministry of Food and Drug Safety, Busan 47537, Republic of KoreaPesticides & Veterinary Drug Residues Division, National Institute of Food & Drug Safety Evaluation, Ministry of Food and Drug Safety, Cheongju 28159, Republic of KoreaDepartment of Industrial Chemistry, Pukyong National University, Busan 48513, Republic of KoreaThe development of efficient methods for evaluating pesticide residues is essential in order to ensure the safety and quality of agricultural products since the Republic of Korea implemented the Positive List System (PLS). The objective of this research was to establish a method for the simultaneous analysis of 322 pesticide residues in fruits and vegetables (such as coffee, potato, corn, and chili pepper), using the quick, easy, cheap, effective, rugged, and safe (QuEChERS) approach in combination with gas chromatography-tandem mass spectrometry (GC-MS/MS). This study introduces a robust, high-throughput GC-MS/MS method for screening the target pesticide residues in agricultural products, achieving the PLS criterion of 0.01 mg/kg LOQ. Despite some compounds not aligning with the CODEX recovery guideline, sufficient reproducibility was confirmed, attesting to the method’s applicability in qualitative analyses. A health risk assessment conducted using estimated daily intake/acceptable daily intake ratios indicated low risks associated with product consumption (<0.035391%), thereby confirming their safety. This efficient method holds significant implications for the safe distribution of agricultural products, including during import inspections.https://www.mdpi.com/2304-8158/12/16/3001multiresidue pesticide analysisfood safetyQuEChERSagricultural productmass spectrometry |
| spellingShingle | Byong-Sun Choi Dong-Uk Lee Woo-Seong Kim Chan-Woong Park Won-Jo Choe Myung-Jun Moon Simultaneous Screening of 322 Residual Pesticides in Fruits and Vegetables Using GC-MS/MS and Deterministic Health Risk Assessments Foods multiresidue pesticide analysis food safety QuEChERS agricultural product mass spectrometry |
| title | Simultaneous Screening of 322 Residual Pesticides in Fruits and Vegetables Using GC-MS/MS and Deterministic Health Risk Assessments |
| title_full | Simultaneous Screening of 322 Residual Pesticides in Fruits and Vegetables Using GC-MS/MS and Deterministic Health Risk Assessments |
| title_fullStr | Simultaneous Screening of 322 Residual Pesticides in Fruits and Vegetables Using GC-MS/MS and Deterministic Health Risk Assessments |
| title_full_unstemmed | Simultaneous Screening of 322 Residual Pesticides in Fruits and Vegetables Using GC-MS/MS and Deterministic Health Risk Assessments |
| title_short | Simultaneous Screening of 322 Residual Pesticides in Fruits and Vegetables Using GC-MS/MS and Deterministic Health Risk Assessments |
| title_sort | simultaneous screening of 322 residual pesticides in fruits and vegetables using gc ms ms and deterministic health risk assessments |
| topic | multiresidue pesticide analysis food safety QuEChERS agricultural product mass spectrometry |
| url | https://www.mdpi.com/2304-8158/12/16/3001 |
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