The differences in tuberculosis notifications and outcomes among males and females in Colombo, Sri Lanka

Introduction: More males than females are reported with tuberculosis (TB). Assessment of disparities between the two groups would permit adopting targeted interventions. Objectives: To describe the differences in notification rates, sputum investigations and treatment outcomes of male and female TB...

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Main Authors: Chandima Hemachandra, Sudath Samaraweera, Arunasalam Pathmeswaran
Format: Article
Language:English
Published: College of Community Physicians of Sri Lanka 2023-10-01
Series:Journal of the College of Community Physicians
Subjects:
Online Access:https://account.jccpsl.sljol.info/index.php/sljo-j-jccpsl/article/view/8614
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author Chandima Hemachandra
Sudath Samaraweera
Arunasalam Pathmeswaran
author_facet Chandima Hemachandra
Sudath Samaraweera
Arunasalam Pathmeswaran
author_sort Chandima Hemachandra
collection DOAJ
description Introduction: More males than females are reported with tuberculosis (TB). Assessment of disparities between the two groups would permit adopting targeted interventions. Objectives: To describe the differences in notification rates, sputum investigations and treatment outcomes of male and female TB patients Methods: A descriptive follow-up study was conducted among 2169 adult TB patients registered in the Colombo District Tuberculosis Register using registry data. Comparisons were made between males and females using Chi-squared test and risk ratio (RR). Results: Males had a higher TB notification rate (161 per 100 000) than females (79 per 100 000) and the highest notification rates were observed in 65-74-year-old age category in both groups. A higher proportion of males than females had pulmonary TB (78.2% in males and 59.7% in females; p<0.05). More males than females had a positive (RR=1.09; 95% CI: 1.05, 1.13) or high-grade sputum smear result (RR=1.15; 95% CI: 1.01, 1.31). Both groups had similar sputum conversion rates at the end of acute phase (80.4% vs. 84.1%). More males were lost to follow up compared to females (10.7% vs. 3.1%, p<0.05). Conclusions & Recommendations: The observed differences between males and females highlight the need to examine TB data disaggregated by sex and to have more sensitive diagnostics for females.
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spelling doaj.art-befa7f5ff74b49599d33024bdc86c7602024-01-09T12:13:38ZengCollege of Community Physicians of Sri LankaJournal of the College of Community Physicians1391-31742579-14512023-10-0129310.4038/jccpsl.v29i3.8614293The differences in tuberculosis notifications and outcomes among males and females in Colombo, Sri LankaChandima Hemachandra0Sudath Samaraweera1Arunasalam Pathmeswaran2Ministry of HealthMinistry of HealthUniversity of Kelaniya Introduction: More males than females are reported with tuberculosis (TB). Assessment of disparities between the two groups would permit adopting targeted interventions. Objectives: To describe the differences in notification rates, sputum investigations and treatment outcomes of male and female TB patients Methods: A descriptive follow-up study was conducted among 2169 adult TB patients registered in the Colombo District Tuberculosis Register using registry data. Comparisons were made between males and females using Chi-squared test and risk ratio (RR). Results: Males had a higher TB notification rate (161 per 100 000) than females (79 per 100 000) and the highest notification rates were observed in 65-74-year-old age category in both groups. A higher proportion of males than females had pulmonary TB (78.2% in males and 59.7% in females; p<0.05). More males than females had a positive (RR=1.09; 95% CI: 1.05, 1.13) or high-grade sputum smear result (RR=1.15; 95% CI: 1.01, 1.31). Both groups had similar sputum conversion rates at the end of acute phase (80.4% vs. 84.1%). More males were lost to follow up compared to females (10.7% vs. 3.1%, p<0.05). Conclusions & Recommendations: The observed differences between males and females highlight the need to examine TB data disaggregated by sex and to have more sensitive diagnostics for females. https://account.jccpsl.sljol.info/index.php/sljo-j-jccpsl/article/view/8614GenderNotification ratesSputum investigationsTreatment outcomesTuberculosis
spellingShingle Chandima Hemachandra
Sudath Samaraweera
Arunasalam Pathmeswaran
The differences in tuberculosis notifications and outcomes among males and females in Colombo, Sri Lanka
Journal of the College of Community Physicians
Gender
Notification rates
Sputum investigations
Treatment outcomes
Tuberculosis
title The differences in tuberculosis notifications and outcomes among males and females in Colombo, Sri Lanka
title_full The differences in tuberculosis notifications and outcomes among males and females in Colombo, Sri Lanka
title_fullStr The differences in tuberculosis notifications and outcomes among males and females in Colombo, Sri Lanka
title_full_unstemmed The differences in tuberculosis notifications and outcomes among males and females in Colombo, Sri Lanka
title_short The differences in tuberculosis notifications and outcomes among males and females in Colombo, Sri Lanka
title_sort differences in tuberculosis notifications and outcomes among males and females in colombo sri lanka
topic Gender
Notification rates
Sputum investigations
Treatment outcomes
Tuberculosis
url https://account.jccpsl.sljol.info/index.php/sljo-j-jccpsl/article/view/8614
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