Role of NRF2 in Colorectal Cancer Prevention and Treatment

Role of NRF2 in Colorectal Cancer Prevention and Treatment

Nuclear factor erythroid 2-related factor 2 (NRF2) is a basic leucine zipper protein that participates in a complex regulatory network in the body. The activation of NRF2 can prevent and treat colorectal cancer (CRC). A variety of natural compounds can activate NRF2 to inhibit oxidative stress and i...

Full description

Bibliographic Details
Main Authors:	Jiaxiang Li BS, Dan Wang MS, Yifei Liu MS, Yanhong Zhou PHD
Format:	Article
Language:	English
Published:	SAGE Publishing 2022-12-01
Series:	Technology in Cancer Research & Treatment
Online Access:	https://doi.org/10.1177/15330338221105736

Similar Items

Diverging role of Nrf2 in cancer progression and prevention
by: Lokesh Gambhir, et al.
Published: (2015-01-01)

Nrf2 signaling pathway: current status and potential therapeutic targetable role in human cancers
by: Li Lin, et al.
Published: (2023-09-01)

NRF1 Regulates the Epithelial Mesenchymal Transition of Breast Cancer by Modulating ROS Homeostasis
by: Linjuan Sun BS, et al.
Published: (2023-03-01)

Targeting Colorectal Cancer Stem Cells as an Effective Treatment for Colorectal Cancer
by: Yu-Shui Ma PhD, et al.
Published: (2020-07-01)

Dual roles of NRF2 in tumor prevention and progression: possible implications in cancer treatment
by: Moon, EJ, et al.
Published: (2014)

Targeting Nrf2 Signaling Pathway in Cancer Prevention and Treatment: The Role of Cannabis Compounds
by: Anna Rybarczyk, et al.
Published: (2023-11-01)

The role of Nrf2-Keap1 axis in colorectal cancer, progression, and chemoresistance
by: Mohammad Reza Sadeghi, et al.
Published: (2017-05-01)

Colorectal Cancer Detected by Machine Learning Models Using Conventional Laboratory Test Data
by: Hui Li MS, et al.
Published: (2021-11-01)

Role of Curcumin in Prevention and Treatment of Colorectal Cancer: The Mechanisms
by: Reyhaneh Moradi-Marjaneh, et al.
Published: (2017-10-01)

Roles of CNC Transcription Factors NRF1 and NRF2 in Cancer
by: Hiroki Sekine, et al.
Published: (2021-02-01)

Role of NRF2 in Ovarian Cancer
by: Giovanni Tossetta, et al.
Published: (2022-03-01)

Role of NRF2 in Lung Cancer
by: Miriam Sánchez-Ortega, et al.
Published: (2021-07-01)

Role of Nrf2 in Pancreatic Cancer
by: Marta Cykowiak, et al.
Published: (2021-12-01)

The NRF2 transcription factor plays a dual role in colorectal cancer: A systematic review.
by: C Gonzalez-Donquiles, et al.
Published: (2017-01-01)

Role of Nrf2 Signaling Cascade in Breast Cancer: Strategies and Treatment
by: Hitesh Kumar, et al.
Published: (2022-04-01)

The Role of the Nrf2/ARE Antioxidant System in Preventing Cardiovascular Diseases
by: Robert E. Smith, et al.
Published: (2016-11-01)

Nrf2 inhibition increases sensitivity to chemotherapy of colorectal cancer by promoting ferroptosis and pyroptosis
by: Yongzhou Huang, et al.
Published: (2023-09-01)

Role of Oxidative Stress and Nrf2/KEAP1 Signaling in Colorectal Cancer: Mechanisms and Therapeutic Perspectives with Phytochemicals
by: Da-Young Lee, et al.
Published: (2021-05-01)

An update of Nrf2 activators and inhibitors in cancer prevention/promotion
by: Farhad Pouremamali, et al.
Published: (2022-06-01)

The role of Nrf2 in the pathogenesis and treatment of ulcerative colitis
by: Shuai Peng, et al.
Published: (2023-06-01)

Blockage of Nrf2 and autophagy by L-selenocystine induces selective death in Nrf2-addicted colorectal cancer cells through p62-Keap-1-Nrf2 axis
by: Wei-Lun Hsu, et al.
Published: (2022-12-01)

Targeting Nrf2 and NF-κB Signaling Pathways in Cancer Prevention: The Role of Apple Phytochemicals
by: Francesca Gado, et al.
Published: (2023-01-01)

The Diagnosis Significance of Serum Cysteine Protease Inhibitors (CST4) in Colorectal Cancer
by: Meiyuan Huang BS, et al.
Published: (2023-04-01)

The Multifaceted Roles of NRF2 in Cancer: Friend or Foe?
by: Christophe Glorieux, et al.
Published: (2024-01-01)

The Role of Nrf2 Activity in Cancer Development and Progression
by: Alina-Andreea Zimta, et al.
Published: (2019-11-01)

RETRACTED ARTICLE: Ibrutinib facilitates the sensitivity of colorectal cancer cells to ferroptosis through BTK/NRF2 pathway
by: Jin-Feng Zhu, et al.
Published: (2023-02-01)

Retraction Note: Ibrutinib facilitates the sensitivity of colorectal cancer cells to ferroptosis through BTK/NRF2 pathway
by: Jin-Feng Zhu, et al.
Published: (2024-02-01)

The Role of Nrf2 in Hearing Loss
by: Dafei Li, et al.
Published: (2021-04-01)

NRF2 Mediates Therapeutic Resistance to Chemoradiation in Colorectal Cancer through a Metabolic Switch
by: Séan M. O’Cathail, et al.
Published: (2021-08-01)

The effect of Nrf2 deletion on the proteomic signature in a human colorectal cancer cell line
by: Omid Cheraghi, et al.
Published: (2022-09-01)

Nrf2 activation does not affect adenoma development in a mouse model of colorectal cancer
by: Elena V. Knatko, et al.
Published: (2021-09-01)

FOXA2 Suppression by TRIM36 Exerts Anti‐Tumor Role in Colorectal Cancer Via Inducing NRF2/GPX4‐Regulated Ferroptosis
by: Xin Liu, et al.
Published: (2023-12-01)

The Role of Nrf2 in Pulmonary Fibrosis: Molecular Mechanisms and Treatment Approaches
by: Yu Wang, et al.
Published: (2022-08-01)

Roles of Nrf2 in Gastric Cancer: Targeting for Therapeutic Strategies
by: Tahereh Farkhondeh, et al.
Published: (2021-05-01)

Pirin, an Nrf2-Regulated Protein, Is Overexpressed in Human Colorectal Tumors
by: Ying Zhang, et al.
Published: (2022-01-01)

Dietary Polyphenols: Extraction, Identification, Bioavailability, and Role for Prevention and Treatment of Colorectal and Prostate Cancers
by: Naveed Ahmad, et al.
Published: (2022-04-01)

Association of 8q24.21 locus with the risk of colorectal cancer: A systematic review and meta-analysis
by: Haerian, M.S., et al.
Published: (2011)

Chebulic Acid Prevents Hypoxia Insult via Nrf2/ARE Pathway in Ischemic Stroke
by: Rong Zhou, et al.
Published: (2022-12-01)

The Nrf2 induction prevents ferroptosis in Friedreich's Ataxia
by: Piergiorgio La Rosa, et al.
Published: (2021-01-01)

Long noncoding RNA LINC00239 inhibits ferroptosis in colorectal cancer by binding to Keap1 to stabilize Nrf2
by: Yuying Han, et al.
Published: (2022-08-01)