Monitoring of Unfractionated Heparin Therapy in the Intensive Care Unit Using a Point-of-Care aPTT: A Comparative, Longitudinal Observational Study with Laboratory-Based aPTT and Anti-Xa Activity Measurement

Monitoring of Unfractionated Heparin Therapy in the Intensive Care Unit Using a Point-of-Care aPTT: A Comparative, Longitudinal Observational Study with Laboratory-Based aPTT and Anti-Xa Activity Measurement

Continuous intravenous unfractionated heparin (UFH) is administered routinely in the intensive care unit (ICU) for the anticoagulation of patients, and monitoring is performed by the activated partial thromboplastin time (APTT) or anti-Xa activity. However, these strategies are associated with poten...

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Bibliographic Details
Main Authors: Benjamin Lardinois, Michaël Hardy, Isabelle Michaux, Geoffrey Horlait, Thomas Rotens, Hugues Jacqmin, Sarah Lessire, Pierre Bulpa, Alain Dive, François Mullier
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Journal of Clinical Medicine
Subjects:
heparin
monitoring
unfractionated heparin
APTT
POCT
anti-Xa
Online Access:https://www.mdpi.com/2077-0383/11/5/1338

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