Inflammatory Role of Milk Fat Globule–Epidermal Growth Factor VIII in Age‐Associated Arterial Remodeling

Inflammatory Role of Milk Fat Globule–Epidermal Growth Factor VIII in Age‐Associated Arterial Remodeling

Background Age‐associated aortic remodeling includes a marked increase in intimal medial thickness (IMT), associated with signs of inflammation. Although aortic wall milk fat globule–epidermal growth factor VIII (MFG‐E8) increases with age, and is associated with aortic inflammation, it is not known...

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Bibliographic Details
Main Authors: Leng Ni, Lijuan Liu, Wanqu Zhu, Richard Telljohann, Jing Zhang, Robert E. Monticone, Kimberly R. McGraw, Changwei Liu, Christopher H. Morrell, Pablo Garrido‐Gil, Jose Luis Labandeira‐Garcia, Edward G. Lakatta, Mingyi Wang
Format: Article
Language:English
Published: Wiley 2022-09-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
age‐associated aortic remodeling
angiotensin II signaling
inflammation
intimal medial thickening
milk fat globule–epidermal growth factor 8
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.121.022574

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