Extracorporeal life support for management of refractory cardiac or respiratory failure: initial experience in a tertiary centre
<p>Abstract</p> <p>Introduction</p> <p>Extracorporeal Life Support (ECLS) and extracorporeal membrane oxygenation (ECMO) have been indicated as treatment for acute respiratory and/or cardiac failure. Here we describe our first year experience of in-hospital ECLS activit...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2010-05-01
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| Series: | Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine |
| Online Access: | http://www.sjtrem.com/content/18/1/28 |
| _version_ | 1818484611112501248 |
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| author | Lazzeri Chiara Bacci Simona Zagli Giovanni Ciapetti Marco Bonacchi Massimo Pasquini Andrea Bonizzoli Manuela Biondi Simona Cianchi Giovanni Peris Adriano Bernardo Pasquale Mascitelli Erminia Sani Guido Gensini Gian |
| author_facet | Lazzeri Chiara Bacci Simona Zagli Giovanni Ciapetti Marco Bonacchi Massimo Pasquini Andrea Bonizzoli Manuela Biondi Simona Cianchi Giovanni Peris Adriano Bernardo Pasquale Mascitelli Erminia Sani Guido Gensini Gian |
| author_sort | Lazzeri Chiara |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Introduction</p> <p>Extracorporeal Life Support (ECLS) and extracorporeal membrane oxygenation (ECMO) have been indicated as treatment for acute respiratory and/or cardiac failure. Here we describe our first year experience of in-hospital ECLS activity, the operative algorithm and the protocol for centralization of adult patients from district hospitals.</p> <p>Methods</p> <p>At a tertiary referral trauma center (Careggi Teaching Hospital, Florence, Italy), an ECLS program was developed from 2008 by the Emergency Department and Heart and Vessel Department ICUs. The ECLS team consists of an intensivist, a cardiac surgeon, a cardiologist and a perfusionist, all trained in ECLS technique. ECMO support was applied in case of severe acute respiratory distress syndrome (ARDS) not responsive to conventional treatments. The use of veno-arterial (V-A) ECLS for cardiac support was reserved for cases of cardiac shock refractory to standard treatment and cardiac arrests not responding to conventional resuscitation.</p> <p>Results</p> <p>A total of 21 patients were treated with ECLS during the first year of activity. Among them, 13 received ECMO for ARDS (5 H1N1-virus related), with a 62% survival. In one case of post-traumatic ARDS, V-A ECLS support permitted multiple organ donation after cerebral death was confirmed. Patients treated with V-A ECLS due to cardiogenic shock (N = 4) had a survival rate of 50%. No patients on V-A ECLS support after cardiac arrest survived (N = 4).</p> <p>Conclusions</p> <p>In our centre, an ECLS Service was instituted over a relatively limited period of time. A strict collaboration between different specialists can be regarded as a key feature to efficiently implement the process.</p> |
| first_indexed | 2024-12-10T15:57:28Z |
| format | Article |
| id | doaj.art-bf07d145a846405f963c4fe30c6a3e1a |
| institution | Directory Open Access Journal |
| issn | 1757-7241 |
| language | English |
| last_indexed | 2024-12-10T15:57:28Z |
| publishDate | 2010-05-01 |
| publisher | BMC |
| record_format | Article |
| series | Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine |
| spelling | doaj.art-bf07d145a846405f963c4fe30c6a3e1a2022-12-22T01:42:36ZengBMCScandinavian Journal of Trauma, Resuscitation and Emergency Medicine1757-72412010-05-011812810.1186/1757-7241-18-28Extracorporeal life support for management of refractory cardiac or respiratory failure: initial experience in a tertiary centreLazzeri ChiaraBacci SimonaZagli GiovanniCiapetti MarcoBonacchi MassimoPasquini AndreaBonizzoli ManuelaBiondi SimonaCianchi GiovanniPeris AdrianoBernardo PasqualeMascitelli ErminiaSani GuidoGensini Gian<p>Abstract</p> <p>Introduction</p> <p>Extracorporeal Life Support (ECLS) and extracorporeal membrane oxygenation (ECMO) have been indicated as treatment for acute respiratory and/or cardiac failure. Here we describe our first year experience of in-hospital ECLS activity, the operative algorithm and the protocol for centralization of adult patients from district hospitals.</p> <p>Methods</p> <p>At a tertiary referral trauma center (Careggi Teaching Hospital, Florence, Italy), an ECLS program was developed from 2008 by the Emergency Department and Heart and Vessel Department ICUs. The ECLS team consists of an intensivist, a cardiac surgeon, a cardiologist and a perfusionist, all trained in ECLS technique. ECMO support was applied in case of severe acute respiratory distress syndrome (ARDS) not responsive to conventional treatments. The use of veno-arterial (V-A) ECLS for cardiac support was reserved for cases of cardiac shock refractory to standard treatment and cardiac arrests not responding to conventional resuscitation.</p> <p>Results</p> <p>A total of 21 patients were treated with ECLS during the first year of activity. Among them, 13 received ECMO for ARDS (5 H1N1-virus related), with a 62% survival. In one case of post-traumatic ARDS, V-A ECLS support permitted multiple organ donation after cerebral death was confirmed. Patients treated with V-A ECLS due to cardiogenic shock (N = 4) had a survival rate of 50%. No patients on V-A ECLS support after cardiac arrest survived (N = 4).</p> <p>Conclusions</p> <p>In our centre, an ECLS Service was instituted over a relatively limited period of time. A strict collaboration between different specialists can be regarded as a key feature to efficiently implement the process.</p>http://www.sjtrem.com/content/18/1/28 |
| spellingShingle | Lazzeri Chiara Bacci Simona Zagli Giovanni Ciapetti Marco Bonacchi Massimo Pasquini Andrea Bonizzoli Manuela Biondi Simona Cianchi Giovanni Peris Adriano Bernardo Pasquale Mascitelli Erminia Sani Guido Gensini Gian Extracorporeal life support for management of refractory cardiac or respiratory failure: initial experience in a tertiary centre Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine |
| title | Extracorporeal life support for management of refractory cardiac or respiratory failure: initial experience in a tertiary centre |
| title_full | Extracorporeal life support for management of refractory cardiac or respiratory failure: initial experience in a tertiary centre |
| title_fullStr | Extracorporeal life support for management of refractory cardiac or respiratory failure: initial experience in a tertiary centre |
| title_full_unstemmed | Extracorporeal life support for management of refractory cardiac or respiratory failure: initial experience in a tertiary centre |
| title_short | Extracorporeal life support for management of refractory cardiac or respiratory failure: initial experience in a tertiary centre |
| title_sort | extracorporeal life support for management of refractory cardiac or respiratory failure initial experience in a tertiary centre |
| url | http://www.sjtrem.com/content/18/1/28 |
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