Vancomycin induced cardiac arrest: a case report
Abstract Background Rapid intravenous administration of vancomycin may manifest with histaminergic responses with clinical features ranging from mild rashes, pruritus and even shock. This case reports of a child, who was accidentally given intravenous vancomycin within minutes and had a cardiac arre...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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BMC
2021-02-01
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| Series: | Journal of Medical Case Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13256-020-02639-8 |
| _version_ | 1818878288913760256 |
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| author | Sharad Khakurel Sangam Rawal |
| author_facet | Sharad Khakurel Sangam Rawal |
| author_sort | Sharad Khakurel |
| collection | DOAJ |
| description | Abstract Background Rapid intravenous administration of vancomycin may manifest with histaminergic responses with clinical features ranging from mild rashes, pruritus and even shock. This case reports of a child, who was accidentally given intravenous vancomycin within minutes and had a cardiac arrest. Case presentation A 9-year-old Asian girl who was scheduled for a limb salvage surgery, received vancomycin preoperatively. As a result of rapid infusion of the drug, the patient developed flushing, pruritus and had respiratory distress with hypotension leading to asystole. However, prompt detection and immediate cardiopulmonary resuscitation revived the patient in time following which sound recovery ensued. We recognised inadvertent brisk infusion of vancomycin as the culprit with strong suspicion of Red Man Syndrome. Conclusion Red Man Syndrome, though rarely encountered, can always be life threatening. With a surge in the use of vancomycin, adverse effects associated with its use also rises. So a comprehensive knowledge regarding its rationale use, adverse effects and its prompt management in personnel prescribing it, can be life saving. |
| first_indexed | 2024-12-19T14:11:48Z |
| format | Article |
| id | doaj.art-bf08f50bd0cc47db85f3b3e33fad0608 |
| institution | Directory Open Access Journal |
| issn | 1752-1947 |
| language | English |
| last_indexed | 2024-12-19T14:11:48Z |
| publishDate | 2021-02-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Medical Case Reports |
| spelling | doaj.art-bf08f50bd0cc47db85f3b3e33fad06082022-12-21T20:18:07ZengBMCJournal of Medical Case Reports1752-19472021-02-011511310.1186/s13256-020-02639-8Vancomycin induced cardiac arrest: a case reportSharad Khakurel0Sangam Rawal1Department of Anesthesiology and Intensive Care, National Trauma Centre, National Academy of Medical SciencesDepartment of Anesthesiology and Intensive Care, National Trauma CentreAbstract Background Rapid intravenous administration of vancomycin may manifest with histaminergic responses with clinical features ranging from mild rashes, pruritus and even shock. This case reports of a child, who was accidentally given intravenous vancomycin within minutes and had a cardiac arrest. Case presentation A 9-year-old Asian girl who was scheduled for a limb salvage surgery, received vancomycin preoperatively. As a result of rapid infusion of the drug, the patient developed flushing, pruritus and had respiratory distress with hypotension leading to asystole. However, prompt detection and immediate cardiopulmonary resuscitation revived the patient in time following which sound recovery ensued. We recognised inadvertent brisk infusion of vancomycin as the culprit with strong suspicion of Red Man Syndrome. Conclusion Red Man Syndrome, though rarely encountered, can always be life threatening. With a surge in the use of vancomycin, adverse effects associated with its use also rises. So a comprehensive knowledge regarding its rationale use, adverse effects and its prompt management in personnel prescribing it, can be life saving.https://doi.org/10.1186/s13256-020-02639-8IntravenousVancomycinRed Man SyndromeCardiac arrest |
| spellingShingle | Sharad Khakurel Sangam Rawal Vancomycin induced cardiac arrest: a case report Journal of Medical Case Reports Intravenous Vancomycin Red Man Syndrome Cardiac arrest |
| title | Vancomycin induced cardiac arrest: a case report |
| title_full | Vancomycin induced cardiac arrest: a case report |
| title_fullStr | Vancomycin induced cardiac arrest: a case report |
| title_full_unstemmed | Vancomycin induced cardiac arrest: a case report |
| title_short | Vancomycin induced cardiac arrest: a case report |
| title_sort | vancomycin induced cardiac arrest a case report |
| topic | Intravenous Vancomycin Red Man Syndrome Cardiac arrest |
| url | https://doi.org/10.1186/s13256-020-02639-8 |
| work_keys_str_mv | AT sharadkhakurel vancomycininducedcardiacarrestacasereport AT sangamrawal vancomycininducedcardiacarrestacasereport |