Efficacy of electrical acupuncture on vascular cognitive impairment with no dementia: study protocol for a randomized controlled trial
Abstract Background Vascular cognitive impairment with no dementia (VCIND), manifested mainly as mild impairment of concentration and executive function, is the early phase of vascular dementia (VD). Currently, there is no specific treatment for VCIND. We hypothesize that electrical acupuncture can...
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| Format: | Article |
| Language: | English |
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BMC
2018-01-01
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| Series: | Trials |
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| Online Access: | http://link.springer.com/article/10.1186/s13063-018-2458-1 |
| _version_ | 1818942947791470592 |
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| author | Tian Li Huangan Wu Franscisca Soto-Aguliar Li Huang Wentao Li Lixing Lao Shifen Xu |
| author_facet | Tian Li Huangan Wu Franscisca Soto-Aguliar Li Huang Wentao Li Lixing Lao Shifen Xu |
| author_sort | Tian Li |
| collection | DOAJ |
| description | Abstract Background Vascular cognitive impairment with no dementia (VCIND), manifested mainly as mild impairment of concentration and executive function, is the early phase of vascular dementia (VD). Currently, there is no specific treatment for VCIND. We hypothesize that electrical acupuncture can improve the mental and motor functions of patients with VCIND. Thus, we designed this randomized controlled trial to test this hypothesis by comparing the therapeutic effect of electrical acupuncture versus sham acupuncture in patients with VCIND. Method/Design In this single-center 3-year study, 120 eligible patients will be recruited and randomly assigned to receive electrical acupuncture treatment (n = 60) or sham acupuncture (n = 60) for 8 consecutive weeks (24 sessions in total), with the same acupoint prescription (DU20, EX-HN3, DU24, DU17, DU26, EX-HN1, HT7, PC6, GB20, SP6). The primary assessment is the Montreal Cognitive Assessment. The secondary assessments are the Modified Barthel Index and Event-Related Potential. All outcomes will be assessed at baseline, endpoint, and follow-up at 8 and 24 weeks after the end of treatment. Discussion If the outcome confirms the effectiveness and safety of electrical acupuncture in treating VCIND, this treatment is expected to be promoted in clinical practice to treat such patients. Trial Registration Chinese Clinical Trial Registry identifier: ChiCTR-IIR-17011513 ; Registered on 27 May 2017. |
| first_indexed | 2024-12-20T07:19:32Z |
| format | Article |
| id | doaj.art-bf0a98cd90974a838bb09f36e8c2a6b0 |
| institution | Directory Open Access Journal |
| issn | 1745-6215 |
| language | English |
| last_indexed | 2024-12-20T07:19:32Z |
| publishDate | 2018-01-01 |
| publisher | BMC |
| record_format | Article |
| series | Trials |
| spelling | doaj.art-bf0a98cd90974a838bb09f36e8c2a6b02022-12-21T19:48:43ZengBMCTrials1745-62152018-01-011911610.1186/s13063-018-2458-1Efficacy of electrical acupuncture on vascular cognitive impairment with no dementia: study protocol for a randomized controlled trialTian Li0Huangan Wu1Franscisca Soto-Aguliar2Li Huang3Wentao Li4Lixing Lao5Shifen Xu6Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese MedicineShanghai Research Institute of Acupuncture and Meridian, Shanghai University of Traditional Chinese MedicineShanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese MedicineShanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese MedicineShanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese MedicineUniversity of Maryland School of MedicineShanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese MedicineAbstract Background Vascular cognitive impairment with no dementia (VCIND), manifested mainly as mild impairment of concentration and executive function, is the early phase of vascular dementia (VD). Currently, there is no specific treatment for VCIND. We hypothesize that electrical acupuncture can improve the mental and motor functions of patients with VCIND. Thus, we designed this randomized controlled trial to test this hypothesis by comparing the therapeutic effect of electrical acupuncture versus sham acupuncture in patients with VCIND. Method/Design In this single-center 3-year study, 120 eligible patients will be recruited and randomly assigned to receive electrical acupuncture treatment (n = 60) or sham acupuncture (n = 60) for 8 consecutive weeks (24 sessions in total), with the same acupoint prescription (DU20, EX-HN3, DU24, DU17, DU26, EX-HN1, HT7, PC6, GB20, SP6). The primary assessment is the Montreal Cognitive Assessment. The secondary assessments are the Modified Barthel Index and Event-Related Potential. All outcomes will be assessed at baseline, endpoint, and follow-up at 8 and 24 weeks after the end of treatment. Discussion If the outcome confirms the effectiveness and safety of electrical acupuncture in treating VCIND, this treatment is expected to be promoted in clinical practice to treat such patients. Trial Registration Chinese Clinical Trial Registry identifier: ChiCTR-IIR-17011513 ; Registered on 27 May 2017.http://link.springer.com/article/10.1186/s13063-018-2458-1Vascular cognitive impairment with no dementia (VCIND)Vascular dementia (VD)Electrical acupuncture |
| spellingShingle | Tian Li Huangan Wu Franscisca Soto-Aguliar Li Huang Wentao Li Lixing Lao Shifen Xu Efficacy of electrical acupuncture on vascular cognitive impairment with no dementia: study protocol for a randomized controlled trial Trials Vascular cognitive impairment with no dementia (VCIND) Vascular dementia (VD) Electrical acupuncture |
| title | Efficacy of electrical acupuncture on vascular cognitive impairment with no dementia: study protocol for a randomized controlled trial |
| title_full | Efficacy of electrical acupuncture on vascular cognitive impairment with no dementia: study protocol for a randomized controlled trial |
| title_fullStr | Efficacy of electrical acupuncture on vascular cognitive impairment with no dementia: study protocol for a randomized controlled trial |
| title_full_unstemmed | Efficacy of electrical acupuncture on vascular cognitive impairment with no dementia: study protocol for a randomized controlled trial |
| title_short | Efficacy of electrical acupuncture on vascular cognitive impairment with no dementia: study protocol for a randomized controlled trial |
| title_sort | efficacy of electrical acupuncture on vascular cognitive impairment with no dementia study protocol for a randomized controlled trial |
| topic | Vascular cognitive impairment with no dementia (VCIND) Vascular dementia (VD) Electrical acupuncture |
| url | http://link.springer.com/article/10.1186/s13063-018-2458-1 |
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