Postoperative Cognitive Dysfunction and Alzheimer’s Disease: A Transcriptome-Based Comparison of Animal Models

Postoperative Cognitive Dysfunction and Alzheimer’s Disease: A Transcriptome-Based Comparison of Animal Models

BackgroundPostoperative cognitive dysfunction (POCD) is a common complication characterized by a significant cognitive decline. Increasing evidence suggests an association between the pathogenesis of POCD and Alzheimer’s disease (AD). However, a comprehensive understanding of their relationships is...

Full description

Bibliographic Details
Main Authors:	Yi-Wei Wang, Liang Wang, Sheng-Jie Yuan, Yuan Zhang, Xin Zhang, Le-Ting Zhou
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-06-01
Series:	Frontiers in Aging Neuroscience
Subjects:	postoperative cognitive dysfunction Alzheimer’s disease bioinformatics transcriptomics high throughput data
Online Access:	https://www.frontiersin.org/articles/10.3389/fnagi.2022.900350/full

Similar Items

Retinoic Acid Receptor Is a Novel Therapeutic Target for Postoperative Cognitive Dysfunction
by: Yongjie Bao, et al.
Published: (2023-09-01)

Decoding competitive endogenous RNA regulatory network in postoperative cognitive dysfunction
by: Wei Wang, et al.
Published: (2022-09-01)

Neuroinflammation: The central enabler of postoperative cognitive dysfunction
by: Yang Liu, et al.
Published: (2023-11-01)

Biomarkers of postoperative delirium and cognitive dysfunction
by: Ganna eAndrosova, et al.
Published: (2015-06-01)

Risk factors for early postoperative cognitive dysfunction after colorectal surgery
by: Yuan Zhang, et al.
Published: (2019-01-01)

Dexmedetomidine ameliorates postoperative cognitive dysfunction by inhibiting Toll‐like receptor 4 signaling in aged mice
by: Xue‐Yue Zhou, et al.
Published: (2020-09-01)

Protective Effect of Celecoxib on Early Postoperative Cognitive Dysfunction in Geriatric Patients
by: Yangzi Zhu, et al.
Published: (2018-08-01)

Electroacupuncture relieves postoperative cognitive dysfunction in elderly rats via regulating amp-activated protein kinase autophagy signaling
by: Cong Niu, et al.
Published: (2022-01-01)

Exploring potential genes and mechanisms linking erectile dysfunction and depression
by: Penghui Yuan, et al.
Published: (2023-12-01)

Management strategies of postoperative gastrointestinal tract dysfunction:a review of 210 cases
by: Lue Wang, et al.
Published: (2022-01-01)

Nomogram to predict postoperative cognitive dysfunction in elderly patients undergoing gastrointestinal tumor resection
by: Huifan Huang, et al.
Published: (2022-10-01)

Update on the Mechanism and Treatment of Sevoflurane-Induced Postoperative Cognitive Dysfunction
by: Cong-mei Wang, et al.
Published: (2021-07-01)

Postoperative cognitive dysfunction: physiopathological aspects and clinical evidence
by: Ghenadie Severin
Published: (2019-03-01)

H3 antagonists and postoperative cognitive dysfunction
by: Chandrasekhar Krishnamurti
Published: (2019-01-01)

SIRT3 Enhances the Protective Role of Propofol in Postoperative Cognitive Dysfunction via Activating Autophagy Mediated by AMPK/mTOR Pathway
by: Shang Li, et al.
Published: (2022-11-01)

Mechanisms of hypoxia in the hippocampal CA3 region in postoperative cognitive dysfunction after cardiopulmonary bypass
by: Ting Liu, et al.
Published: (2022-05-01)

Mannose-coated superparamagnetic iron oxide nanozyme for preventing postoperative cognitive dysfunction
by: Qianyun Zhu, et al.
Published: (2023-04-01)

Postoperative cognitive recovery and prevention of postoperative cognitive complications in the elderly patient
by: Hisham A Almuzayyen, et al.
Published: (2023-01-01)

Effect of Electroacupuncture on Inflammation Response and Ferroptosis in Rats Modeling Postoperative Cognitive Dysfunction
by: QIN Xiaoyu, ZHANG Binsen, ZHANG Xiaojia, LU Xiaoting, LIU Hongxin, WANG Chunai
Published: (2024-02-01)

Intravenous infusion of dexmedetomidine during the surgery to prevent postoperative delirium and postoperative cognitive dysfunction undergoing non-cardiac surgery: a meta-analysis of randomized controlled trials
by: Di Wang, et al.
Published: (2024-04-01)

The effect of intravenous lidocaine on postoperative cognitive dysfunction: a systematic review and meta-analysis
by: Chuan Geng, et al.
Published: (2023-09-01)

Postoperative cognitive dysfunctions and operating position
by: K.I. Lyzogub, et al.
Published: (2022-05-01)

Tregs dysfunction aggravates postoperative cognitive impairment in aged mice
by: Yile Zhou, et al.
Published: (2023-03-01)

Postoperative Cognitive Dysfunction after Coronary Artery Bypass Grafting
by: Shi-Min Yuan, et al.

Acute pre-operative ibuprofen improves cognition in a rat model for postoperative cognitive dysfunction
by: Klaske Oberman, et al.
Published: (2021-07-01)

The involvement of the gut microbiota in postoperative cognitive dysfunction based on integrated metagenomic and metabolomics analysis
by: Shi-hua Zhang, et al.
Published: (2023-12-01)

Identification of the Potential Key Circular RNAs in Elderly Patients With Postoperative Cognitive Dysfunction
by: Rui Gao, et al.
Published: (2020-06-01)

Anesthesia and Alzheimer disease – Current perceptions
by: Ana Filipa Vieira da Silva Ferreira Marques, et al.

Effects of perioperative cognitive function training on postoperative cognitive dysfunction and postoperative delirium: a systematic review and meta-analysis
by: Li Zhao, et al.
Published: (2023-06-01)

Establishment of prediction model for risk of postoperative cognitive dysfunction after non-cardiac surgery based on different machine learning algorithms
by: SONG Ailin, et al.
Published: (2023-04-01)

Olanzapine attenuates postoperative cognitive dysfunction in adult rats
by: Keitaro Tachi, et al.
Published: (2021-02-01)

Cerebral Mast Cells Participate In Postoperative Cognitive Dysfunction by Promoting Astrocyte Activation
by: Xiang Zhang, et al.
Published: (2016-11-01)

The effect of Dexmedetomidine on the incidence of postoperative cognitive dysfunction in elderly patients after prolonged abdominal surgery
by: Sahar Mohamed, et al.
Published: (2014-10-01)

The incidence of postoperative cognitive dysfunction in elderly patients underwent elective surgery at Sanglah General Hospital
by: Pontisomaya Parami, et al.
Published: (2020-01-01)

The Effect and Optimal Dosage of Dexmedetomidine Plus Sufentanil for Postoperative Analgesia in Elderly Patients With Postoperative Delirium and Early Postoperative Cognitive Dysfunction: A Single-Center, Prospective, Randomized, Double-Blind, Controlled Trial
by: Wenshuai Zhao, et al.
Published: (2020-10-01)

Effect of Preoperative Dexmedetomidine on Prevalence of Postoperative Cognitive Dysfunction in Elderly Patients Candidate for Orthopedic Surgery under General Anesthesia
by: Alireza Pournajafian, et al.
Published: (2020-11-01)

Effect of postoperative cognitive dysfunction on rehabilitation of patients after cardiac valve replacement surgery
by: DUAN Zhenxin, et al.
Published: (2019-06-01)

Ru360 Alleviates Postoperative Cognitive Dysfunction in Aged Mice by Inhibiting MCU-Mediated Mitochondrial Dysfunction
by: Xu X, et al.
Published: (2023-07-01)

Dual roles of anesthetics in postoperative cognitive dysfunction: Regulation of microglial activation through inflammatory signaling pathways
by: Mengxue Zhang, et al.
Published: (2023-01-01)

Association of Olfactory Impairment and Postoperative Cognitive Dysfunction in Elderly Patients
by: Yang Lan, et al.
Published: (2021-04-01)