Self-Reported Onset of Paroxysmal Atrial Fibrillation Is Related to Sleeping Body Position
Background: Because stretch of the atrial myocardium is proarrhythmic for atrial fibrillation (AF) and a left lateral body position increases atrial dimensions in humans, we hypothesized that left lateral recumbence is a frequent AF-triggering body position in AF patients.Methods: We performed a que...
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Frontiers Media S.A.
2021-07-01
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| Series: | Frontiers in Physiology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fphys.2021.708650/full |
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| author | Lisa A. Gottlieb Lisa A. Gottlieb Lorena Sanchez y Blanco Lorena Sanchez y Blanco Mélèze Hocini Mélèze Hocini Lukas R. C. Dekker Lukas R. C. Dekker Ruben Coronel Ruben Coronel |
| author_facet | Lisa A. Gottlieb Lisa A. Gottlieb Lorena Sanchez y Blanco Lorena Sanchez y Blanco Mélèze Hocini Mélèze Hocini Lukas R. C. Dekker Lukas R. C. Dekker Ruben Coronel Ruben Coronel |
| author_sort | Lisa A. Gottlieb |
| collection | DOAJ |
| description | Background: Because stretch of the atrial myocardium is proarrhythmic for atrial fibrillation (AF) and a left lateral body position increases atrial dimensions in humans, we hypothesized that left lateral recumbence is a frequent AF-triggering body position in AF patients.Methods: We performed a questionnaire study of symptomatic paroxysmal AF (episodes of AF < 1 week) patients scheduled for a first AF ablation therapy at Catharina Hospital, Eindhoven, the Netherlands and at University Hospital, Bordeaux, France.Results: Ninety-four symptomatic paroxysmal AF patients were included [mean age 61 ± 11 years, median AF history of 29(48) months, 31% were females]. Twenty-two percent of patients reported a specific body position as a trigger of their AF symptoms. The triggering body position was left lateral position in 57% of cases, supine position in 33%, right lateral position in 10%, and prone position in 5% (p = 0.003 overall difference in prevalence). Patients with positional AF had a higher body mass index compared to patients without nocturnal/positional AF [28.7(4.2) and 25.4(5.2) kg/m2, respectively, p = 0.025], but otherwise resembled these patients.Conclusion: Body position, and the left lateral position, in particular, is a common trigger of AF in symptomatic AF patients. Moreover, positional AF is associated with overweight. Understanding of the underlying mechanisms of positional AF can contribute to AF treatment and prevention. |
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| language | English |
| last_indexed | 2024-12-17T07:38:21Z |
| publishDate | 2021-07-01 |
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| series | Frontiers in Physiology |
| spelling | doaj.art-bf0d28a7f50e488eb8ece6d7d884f5f32022-12-21T21:58:15ZengFrontiers Media S.A.Frontiers in Physiology1664-042X2021-07-011210.3389/fphys.2021.708650708650Self-Reported Onset of Paroxysmal Atrial Fibrillation Is Related to Sleeping Body PositionLisa A. Gottlieb0Lisa A. Gottlieb1Lorena Sanchez y Blanco2Lorena Sanchez y Blanco3Mélèze Hocini4Mélèze Hocini5Lukas R. C. Dekker6Lukas R. C. Dekker7Ruben Coronel8Ruben Coronel9Institut de rythmologie et modélisation cardiaque (IHU Liryc), University of Bordeaux, Pessac, FranceDepartment of Experimental Cardiology, Academic Medical Center, Amsterdam University Medical Center (AUMC), Amsterdam, NetherlandsInstitut de rythmologie et modélisation cardiaque (IHU Liryc), University of Bordeaux, Pessac, FranceDepartment of Cardiology, University Hospital, Bordeaux, Pessac, FranceInstitut de rythmologie et modélisation cardiaque (IHU Liryc), University of Bordeaux, Pessac, FranceDepartment of Cardiology, University Hospital, Bordeaux, Pessac, FranceDepartment of Biomedical Engineering, University of Technology, Eindhoven, NetherlandsDepartment of Cardiology, Catharina Hospital, Eindhoven, NetherlandsInstitut de rythmologie et modélisation cardiaque (IHU Liryc), University of Bordeaux, Pessac, FranceDepartment of Experimental Cardiology, Academic Medical Center, Amsterdam University Medical Center (AUMC), Amsterdam, NetherlandsBackground: Because stretch of the atrial myocardium is proarrhythmic for atrial fibrillation (AF) and a left lateral body position increases atrial dimensions in humans, we hypothesized that left lateral recumbence is a frequent AF-triggering body position in AF patients.Methods: We performed a questionnaire study of symptomatic paroxysmal AF (episodes of AF < 1 week) patients scheduled for a first AF ablation therapy at Catharina Hospital, Eindhoven, the Netherlands and at University Hospital, Bordeaux, France.Results: Ninety-four symptomatic paroxysmal AF patients were included [mean age 61 ± 11 years, median AF history of 29(48) months, 31% were females]. Twenty-two percent of patients reported a specific body position as a trigger of their AF symptoms. The triggering body position was left lateral position in 57% of cases, supine position in 33%, right lateral position in 10%, and prone position in 5% (p = 0.003 overall difference in prevalence). Patients with positional AF had a higher body mass index compared to patients without nocturnal/positional AF [28.7(4.2) and 25.4(5.2) kg/m2, respectively, p = 0.025], but otherwise resembled these patients.Conclusion: Body position, and the left lateral position, in particular, is a common trigger of AF in symptomatic AF patients. Moreover, positional AF is associated with overweight. Understanding of the underlying mechanisms of positional AF can contribute to AF treatment and prevention.https://www.frontiersin.org/articles/10.3389/fphys.2021.708650/fullatrial fibrillationquestionnairebody positionleft lateral recumbencebody mass index |
| spellingShingle | Lisa A. Gottlieb Lisa A. Gottlieb Lorena Sanchez y Blanco Lorena Sanchez y Blanco Mélèze Hocini Mélèze Hocini Lukas R. C. Dekker Lukas R. C. Dekker Ruben Coronel Ruben Coronel Self-Reported Onset of Paroxysmal Atrial Fibrillation Is Related to Sleeping Body Position Frontiers in Physiology atrial fibrillation questionnaire body position left lateral recumbence body mass index |
| title | Self-Reported Onset of Paroxysmal Atrial Fibrillation Is Related to Sleeping Body Position |
| title_full | Self-Reported Onset of Paroxysmal Atrial Fibrillation Is Related to Sleeping Body Position |
| title_fullStr | Self-Reported Onset of Paroxysmal Atrial Fibrillation Is Related to Sleeping Body Position |
| title_full_unstemmed | Self-Reported Onset of Paroxysmal Atrial Fibrillation Is Related to Sleeping Body Position |
| title_short | Self-Reported Onset of Paroxysmal Atrial Fibrillation Is Related to Sleeping Body Position |
| title_sort | self reported onset of paroxysmal atrial fibrillation is related to sleeping body position |
| topic | atrial fibrillation questionnaire body position left lateral recumbence body mass index |
| url | https://www.frontiersin.org/articles/10.3389/fphys.2021.708650/full |
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