Vestibular dysfunction and its association with cognitive impairment and dementia
The vestibular system plays an important role in maintaining balance and posture. It also contributes to vertical perception, body awareness and spatial navigation. In addition to its sensory function, the vestibular system has direct connections to key areas responsible for higher cognitive functio...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-03-01
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| Series: | Frontiers in Neuroscience |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnins.2024.1304810/full |
| _version_ | 1797243111583252480 |
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| author | Cristian Aedo-Sanchez Patricio Riquelme-Contreras Patricio Riquelme-Contreras Patricio Riquelme-Contreras Patricio Riquelme-Contreras Fernando Henríquez Fernando Henríquez Fernando Henríquez Enzo Aguilar-Vidal |
| author_facet | Cristian Aedo-Sanchez Patricio Riquelme-Contreras Patricio Riquelme-Contreras Patricio Riquelme-Contreras Patricio Riquelme-Contreras Fernando Henríquez Fernando Henríquez Fernando Henríquez Enzo Aguilar-Vidal |
| author_sort | Cristian Aedo-Sanchez |
| collection | DOAJ |
| description | The vestibular system plays an important role in maintaining balance and posture. It also contributes to vertical perception, body awareness and spatial navigation. In addition to its sensory function, the vestibular system has direct connections to key areas responsible for higher cognitive functions, such as the prefrontal cortex, insula and hippocampus. Several studies have reported that vestibular dysfunction, in particular bilateral vestibulopathy, is associated with an increased risk of cognitive impairment and the development of dementias such as Alzheimer’s disease. However, it is still controversial whether there is a causal relationship between vestibular damage and cognitive dysfunction. In this mini-review, we will explore the relationship between the vestibular system, cognitive dysfunction and dementia, hypotheses about the hypothesis and causes that may explain this phenomenon and also some potential confounders that may also lead to cognitive impairment. We will also review multimodal neuroimaging approaches that have investigated structural and functional effects on the cortico-vestibular network and finally, describe some approaches to the management of patients with vestibular damage who have shown some cognitive impairment. |
| first_indexed | 2024-04-24T18:49:55Z |
| format | Article |
| id | doaj.art-bf121e9e21094d46abf196e3ef71f605 |
| institution | Directory Open Access Journal |
| issn | 1662-453X |
| language | English |
| last_indexed | 2024-04-24T18:49:55Z |
| publishDate | 2024-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neuroscience |
| spelling | doaj.art-bf121e9e21094d46abf196e3ef71f6052024-03-27T04:28:59ZengFrontiers Media S.A.Frontiers in Neuroscience1662-453X2024-03-011810.3389/fnins.2024.13048101304810Vestibular dysfunction and its association with cognitive impairment and dementiaCristian Aedo-Sanchez0Patricio Riquelme-Contreras1Patricio Riquelme-Contreras2Patricio Riquelme-Contreras3Patricio Riquelme-Contreras4Fernando Henríquez5Fernando Henríquez6Fernando Henríquez7Enzo Aguilar-Vidal8Department of Medical Technology, Faculty of Medicine, Universidad de Chile, Santiago, ChileDepartment of Medical Technology, Faculty of Medicine, Universidad de Chile, Santiago, ChileMemory and Neuropsychiatric Center (CMYN), Department of Neurology, Hospital del Salvador and Faculty of Medicine, Universidad de Chile, Santiago, ChileLaboratory of Neuropsychology and Clinical Neuroscience (LANNEC), Faculty of Medicine, Universidad de Chile, Santiago, ChileGeroscience Center for Brain Health and Metabolism (GERO), Santiago, ChileLaboratory of Neuropsychology and Clinical Neuroscience (LANNEC), Faculty of Medicine, Universidad de Chile, Santiago, ChileGeroscience Center for Brain Health and Metabolism (GERO), Santiago, ChileLaboratory for Cognitive and Evolutionary Neuroscience (LaNCE), Department of Psychiatry, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, ChileDepartment of Medical Technology, Faculty of Medicine, Universidad de Chile, Santiago, ChileThe vestibular system plays an important role in maintaining balance and posture. It also contributes to vertical perception, body awareness and spatial navigation. In addition to its sensory function, the vestibular system has direct connections to key areas responsible for higher cognitive functions, such as the prefrontal cortex, insula and hippocampus. Several studies have reported that vestibular dysfunction, in particular bilateral vestibulopathy, is associated with an increased risk of cognitive impairment and the development of dementias such as Alzheimer’s disease. However, it is still controversial whether there is a causal relationship between vestibular damage and cognitive dysfunction. In this mini-review, we will explore the relationship between the vestibular system, cognitive dysfunction and dementia, hypotheses about the hypothesis and causes that may explain this phenomenon and also some potential confounders that may also lead to cognitive impairment. We will also review multimodal neuroimaging approaches that have investigated structural and functional effects on the cortico-vestibular network and finally, describe some approaches to the management of patients with vestibular damage who have shown some cognitive impairment.https://www.frontiersin.org/articles/10.3389/fnins.2024.1304810/fullvestibulardementiaAlzheimer’s diseasevestibular dysfunctiondizziness |
| spellingShingle | Cristian Aedo-Sanchez Patricio Riquelme-Contreras Patricio Riquelme-Contreras Patricio Riquelme-Contreras Patricio Riquelme-Contreras Fernando Henríquez Fernando Henríquez Fernando Henríquez Enzo Aguilar-Vidal Vestibular dysfunction and its association with cognitive impairment and dementia Frontiers in Neuroscience vestibular dementia Alzheimer’s disease vestibular dysfunction dizziness |
| title | Vestibular dysfunction and its association with cognitive impairment and dementia |
| title_full | Vestibular dysfunction and its association with cognitive impairment and dementia |
| title_fullStr | Vestibular dysfunction and its association with cognitive impairment and dementia |
| title_full_unstemmed | Vestibular dysfunction and its association with cognitive impairment and dementia |
| title_short | Vestibular dysfunction and its association with cognitive impairment and dementia |
| title_sort | vestibular dysfunction and its association with cognitive impairment and dementia |
| topic | vestibular dementia Alzheimer’s disease vestibular dysfunction dizziness |
| url | https://www.frontiersin.org/articles/10.3389/fnins.2024.1304810/full |
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