Correlation Between Tic Disorders and Serum 25-Hydroxyvitamin D Levels in Chinese Children
ObjectiveTo explore the correlation between serum 25-hydroxyvitamin D levels and tic disorders (TDs) in Chinese children.MethodsWe selected 2960 children with TD and 2665 healthy controls, aged 5–14 years, from the Department of Neurology of the Shanghai Children’s Hospital. Serum 25-hydroxyvitamin...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-05-01
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| Series: | Frontiers in Pediatrics |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fped.2022.833371/full |
| _version_ | 1817984722074075136 |
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| author | Simei Wang Quanmei Xu Anqi Wang Fang Yuan Xiaona Luo Yilin Wang Miao Guo Yuanfeng Zhang Wenjing Zhang Xiaobing Ji Yun Ren Yucai Chen |
| author_facet | Simei Wang Quanmei Xu Anqi Wang Fang Yuan Xiaona Luo Yilin Wang Miao Guo Yuanfeng Zhang Wenjing Zhang Xiaobing Ji Yun Ren Yucai Chen |
| author_sort | Simei Wang |
| collection | DOAJ |
| description | ObjectiveTo explore the correlation between serum 25-hydroxyvitamin D levels and tic disorders (TDs) in Chinese children.MethodsWe selected 2960 children with TD and 2665 healthy controls, aged 5–14 years, from the Department of Neurology of the Shanghai Children’s Hospital. Serum 25-hydroxyvitamin D levels and degrees of vitamin D deficiency were compared between patients with TD and healthy children.ResultsThe mean serum 25-hydroxyvitamin D level in the TD group was significantly lower than that in the control group (P < 0.001). The proportion of patients with 25-hydroxyvitamin D deficiency in the TD group was significantly higher than that in the control group. However, there was no correlation between 25-hydroxyvitamin D deficiency and the severity of TD. In addition, for age-wise comparison, mean levels of 25-hydroxyvitamin D and its deficiency in the TD group were the most significant in children over 9 years of age.ConclusionThere is a correlation between 25-hydroxyvitamin D deficiency and TD in Chinese children, but not between 25-hydroxyvitamin D deficiency and the severity of TD. There was a correlation between age and deficiency of 25-hydroxyvitamin D; this deficiency was most pronounced among those over the age of 9 years. |
| first_indexed | 2024-04-13T23:48:26Z |
| format | Article |
| id | doaj.art-bf12387f85394fd2b7937a6e513d084a |
| institution | Directory Open Access Journal |
| issn | 2296-2360 |
| language | English |
| last_indexed | 2024-04-13T23:48:26Z |
| publishDate | 2022-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pediatrics |
| spelling | doaj.art-bf12387f85394fd2b7937a6e513d084a2022-12-22T02:24:13ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602022-05-011010.3389/fped.2022.833371833371Correlation Between Tic Disorders and Serum 25-Hydroxyvitamin D Levels in Chinese ChildrenSimei WangQuanmei XuAnqi WangFang YuanXiaona LuoYilin WangMiao GuoYuanfeng ZhangWenjing ZhangXiaobing JiYun RenYucai ChenObjectiveTo explore the correlation between serum 25-hydroxyvitamin D levels and tic disorders (TDs) in Chinese children.MethodsWe selected 2960 children with TD and 2665 healthy controls, aged 5–14 years, from the Department of Neurology of the Shanghai Children’s Hospital. Serum 25-hydroxyvitamin D levels and degrees of vitamin D deficiency were compared between patients with TD and healthy children.ResultsThe mean serum 25-hydroxyvitamin D level in the TD group was significantly lower than that in the control group (P < 0.001). The proportion of patients with 25-hydroxyvitamin D deficiency in the TD group was significantly higher than that in the control group. However, there was no correlation between 25-hydroxyvitamin D deficiency and the severity of TD. In addition, for age-wise comparison, mean levels of 25-hydroxyvitamin D and its deficiency in the TD group were the most significant in children over 9 years of age.ConclusionThere is a correlation between 25-hydroxyvitamin D deficiency and TD in Chinese children, but not between 25-hydroxyvitamin D deficiency and the severity of TD. There was a correlation between age and deficiency of 25-hydroxyvitamin D; this deficiency was most pronounced among those over the age of 9 years.https://www.frontiersin.org/articles/10.3389/fped.2022.833371/fulltic disordervitaminchildren25-hydroxyvitamin Ddeficiency |
| spellingShingle | Simei Wang Quanmei Xu Anqi Wang Fang Yuan Xiaona Luo Yilin Wang Miao Guo Yuanfeng Zhang Wenjing Zhang Xiaobing Ji Yun Ren Yucai Chen Correlation Between Tic Disorders and Serum 25-Hydroxyvitamin D Levels in Chinese Children Frontiers in Pediatrics tic disorder vitamin children 25-hydroxyvitamin D deficiency |
| title | Correlation Between Tic Disorders and Serum 25-Hydroxyvitamin D Levels in Chinese Children |
| title_full | Correlation Between Tic Disorders and Serum 25-Hydroxyvitamin D Levels in Chinese Children |
| title_fullStr | Correlation Between Tic Disorders and Serum 25-Hydroxyvitamin D Levels in Chinese Children |
| title_full_unstemmed | Correlation Between Tic Disorders and Serum 25-Hydroxyvitamin D Levels in Chinese Children |
| title_short | Correlation Between Tic Disorders and Serum 25-Hydroxyvitamin D Levels in Chinese Children |
| title_sort | correlation between tic disorders and serum 25 hydroxyvitamin d levels in chinese children |
| topic | tic disorder vitamin children 25-hydroxyvitamin D deficiency |
| url | https://www.frontiersin.org/articles/10.3389/fped.2022.833371/full |
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