A study on the effects of the Qihuang Needle therapy on patients with Parkinson's disease
ObjectiveThis study aimed to evaluate the effectiveness of the Qihuang Needle (QHN) in treating Parkinson's disease (PD).Design, setting, and participantsThe trial was an 8-week randomized clinical trial (4 weeks of treatment followed by 4 weeks of follow-up) conducted from January 2021 to July...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2023-01-01
|
| Series: | Frontiers in Neurology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fneur.2022.1022057/full |
| _version_ | 1811176851270270976 |
|---|---|
| author | Xinyu Li Jingpei Zhou Renxiu He Jiahui Lian Jie Jia Chialin Hsu Shihua Yuan Zhenhu Chen |
| author_facet | Xinyu Li Jingpei Zhou Renxiu He Jiahui Lian Jie Jia Chialin Hsu Shihua Yuan Zhenhu Chen |
| author_sort | Xinyu Li |
| collection | DOAJ |
| description | ObjectiveThis study aimed to evaluate the effectiveness of the Qihuang Needle (QHN) in treating Parkinson's disease (PD).Design, setting, and participantsThe trial was an 8-week randomized clinical trial (4 weeks of treatment followed by 4 weeks of follow-up) conducted from January 2021 to July 2022 in outpatient settings at three clinical sites in Guangzhou, China. Thirty-four participants with PD were diagnosed based on the diagnostic criteria formulated by the brain bank of the British Parkinson's Disease Society in 1992.InterventionsPatients in the treatment and control groups received six sessions within 4 weeks of the QHN therapy or the sham acupuncture therapy (two times per week for the first two consecutive weeks and one time per week for the following two consecutive weeks).Main outcomes and measuresThe primary outcome measure was the change in the Parkinson's Disease Rating Scale-Part III Motor Examination (UPDRS III) between baseline and 8 weeks after treatments. Secondary outcome measures were the Non-Motor Symptoms Scale for Parkinson's Disease (NMSS) and Parkinson's Disease Daily Quality of Life-39 (PDQ-39). Real-time shear wave elastography (SWE) was assessed for each patient at baseline and during the 4-week period as the third outcome measure.ResultsA more significant reduction of UPDRS III score, PDQ-39, NMSS, and SWE was observed in the QHN group than in the sham acupuncture group.ConclusionsThe QHN therapy consistently demonstrated superiority and produced clinically meaningful benefits in reducing motor and non-motor symptoms, as well as significantly improving muscle stiffness, in patients with PD. |
| first_indexed | 2024-04-10T19:58:34Z |
| format | Article |
| id | doaj.art-bf15b069fa1b48ccafd97e0b9ae618bc |
| institution | Directory Open Access Journal |
| issn | 1664-2295 |
| language | English |
| last_indexed | 2024-04-10T19:58:34Z |
| publishDate | 2023-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurology |
| spelling | doaj.art-bf15b069fa1b48ccafd97e0b9ae618bc2023-01-27T13:36:56ZengFrontiers Media S.A.Frontiers in Neurology1664-22952023-01-011310.3389/fneur.2022.10220571022057A study on the effects of the Qihuang Needle therapy on patients with Parkinson's diseaseXinyu Li0Jingpei Zhou1Renxiu He2Jiahui Lian3Jie Jia4Chialin Hsu5Shihua Yuan6Zhenhu Chen7Medical College of Acupuncture, Moxibustion, and Rehabilitation, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, ChinaThe First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, ChinaBaiyun Branch of Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, ChinaThe Affiliated Traditional Chinese Medicine Hospital, Guangzhou Medical University, Guangzhou, Guangdong, ChinaDepartment of Ultrasound, The First Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, ChinaInternational College, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, ChinaInternational College, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, ChinaThe First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, ChinaObjectiveThis study aimed to evaluate the effectiveness of the Qihuang Needle (QHN) in treating Parkinson's disease (PD).Design, setting, and participantsThe trial was an 8-week randomized clinical trial (4 weeks of treatment followed by 4 weeks of follow-up) conducted from January 2021 to July 2022 in outpatient settings at three clinical sites in Guangzhou, China. Thirty-four participants with PD were diagnosed based on the diagnostic criteria formulated by the brain bank of the British Parkinson's Disease Society in 1992.InterventionsPatients in the treatment and control groups received six sessions within 4 weeks of the QHN therapy or the sham acupuncture therapy (two times per week for the first two consecutive weeks and one time per week for the following two consecutive weeks).Main outcomes and measuresThe primary outcome measure was the change in the Parkinson's Disease Rating Scale-Part III Motor Examination (UPDRS III) between baseline and 8 weeks after treatments. Secondary outcome measures were the Non-Motor Symptoms Scale for Parkinson's Disease (NMSS) and Parkinson's Disease Daily Quality of Life-39 (PDQ-39). Real-time shear wave elastography (SWE) was assessed for each patient at baseline and during the 4-week period as the third outcome measure.ResultsA more significant reduction of UPDRS III score, PDQ-39, NMSS, and SWE was observed in the QHN group than in the sham acupuncture group.ConclusionsThe QHN therapy consistently demonstrated superiority and produced clinically meaningful benefits in reducing motor and non-motor symptoms, as well as significantly improving muscle stiffness, in patients with PD.https://www.frontiersin.org/articles/10.3389/fneur.2022.1022057/fullacupunctureQihuang Needle therapyParkinsion's diseaserandomized clinical trialsham acupuncture |
| spellingShingle | Xinyu Li Jingpei Zhou Renxiu He Jiahui Lian Jie Jia Chialin Hsu Shihua Yuan Zhenhu Chen A study on the effects of the Qihuang Needle therapy on patients with Parkinson's disease Frontiers in Neurology acupuncture Qihuang Needle therapy Parkinsion's disease randomized clinical trial sham acupuncture |
| title | A study on the effects of the Qihuang Needle therapy on patients with Parkinson's disease |
| title_full | A study on the effects of the Qihuang Needle therapy on patients with Parkinson's disease |
| title_fullStr | A study on the effects of the Qihuang Needle therapy on patients with Parkinson's disease |
| title_full_unstemmed | A study on the effects of the Qihuang Needle therapy on patients with Parkinson's disease |
| title_short | A study on the effects of the Qihuang Needle therapy on patients with Parkinson's disease |
| title_sort | study on the effects of the qihuang needle therapy on patients with parkinson s disease |
| topic | acupuncture Qihuang Needle therapy Parkinsion's disease randomized clinical trial sham acupuncture |
| url | https://www.frontiersin.org/articles/10.3389/fneur.2022.1022057/full |
| work_keys_str_mv | AT xinyuli astudyontheeffectsoftheqihuangneedletherapyonpatientswithparkinsonsdisease AT jingpeizhou astudyontheeffectsoftheqihuangneedletherapyonpatientswithparkinsonsdisease AT renxiuhe astudyontheeffectsoftheqihuangneedletherapyonpatientswithparkinsonsdisease AT jiahuilian astudyontheeffectsoftheqihuangneedletherapyonpatientswithparkinsonsdisease AT jiejia astudyontheeffectsoftheqihuangneedletherapyonpatientswithparkinsonsdisease AT chialinhsu astudyontheeffectsoftheqihuangneedletherapyonpatientswithparkinsonsdisease AT shihuayuan astudyontheeffectsoftheqihuangneedletherapyonpatientswithparkinsonsdisease AT zhenhuchen astudyontheeffectsoftheqihuangneedletherapyonpatientswithparkinsonsdisease AT xinyuli studyontheeffectsoftheqihuangneedletherapyonpatientswithparkinsonsdisease AT jingpeizhou studyontheeffectsoftheqihuangneedletherapyonpatientswithparkinsonsdisease AT renxiuhe studyontheeffectsoftheqihuangneedletherapyonpatientswithparkinsonsdisease AT jiahuilian studyontheeffectsoftheqihuangneedletherapyonpatientswithparkinsonsdisease AT jiejia studyontheeffectsoftheqihuangneedletherapyonpatientswithparkinsonsdisease AT chialinhsu studyontheeffectsoftheqihuangneedletherapyonpatientswithparkinsonsdisease AT shihuayuan studyontheeffectsoftheqihuangneedletherapyonpatientswithparkinsonsdisease AT zhenhuchen studyontheeffectsoftheqihuangneedletherapyonpatientswithparkinsonsdisease |