Interleukin-4 receptor alpha is still required after Th2 polarization for the maintenance and the recall of protective immunity to Nematode infection.

Interleukin-4 receptor alpha is still required after Th2 polarization for the maintenance and the recall of protective immunity to Nematode infection.

There is currently no vaccine against parasitic nematodes and the knowledge on the mechanisms by which protective immunity against this class of parasites is achieved is continuously expanding. Nematode parasites trigger a host protective type 2 immune response via interleukin-4 receptor alpha (IL-4...

書目詳細資料
Main Authors:	Justin Komguep Nono, Hlumani Ndlovu, Nada Abdel Aziz, Thabo Mpotje, Lerato Hlaka, Frank Brombacher
格式:	Article
語言:	English
出版:	Public Library of Science (PLoS) 2017-06-01
叢編:	PLoS Neglected Tropical Diseases
在線閱讀:	http://europepmc.org/articles/PMC5501681?pdf=render

相似書籍

Interleukin-4 Receptor Alpha Expressing B Cells Are Essential to Down-Modulate Host Granulomatous Inflammation During Schistosomasis
由: Hlumani Ndlovu, et al.
出版: (2018-12-01)

Praziquantel Treatment of Schistosoma mansoni Infected Mice Renders Them Less Susceptible to Reinfection
由: Justin Komguep Nono, et al.
出版: (2021-12-01)

Cysteinyl leukotriene receptor-1 as a potential target for host-directed therapy during chronic schistosomiasis in murine model
由: Paballo Mosala, et al.
出版: (2024-05-01)

The Foxp3+ regulatory T-cell population requires IL-4Rα signaling to control inflammation during helminth infections.
由: Nada Abdel Aziz, et al.
出版: (2018-10-01)

Schistosoma mansoni infection induces plasmablast and plasma cell death in the bone marrow and accelerates the decline of host vaccine responses.
由: Fungai Musaigwa, et al.
出版: (2022-02-01)

Host Regulators of Liver Fibrosis During Human Schistosomiasis
由: Severin Donald Kamdem, et al.
出版: (2018-11-01)

Schistosomiasis Burden and Its Association With Lower Measles Vaccine Responses in School Children From Rural Cameroon
由: Justin Komguep Nono, et al.
出版: (2018-10-01)

Inducible deletion of CD28 prior to secondary nippostrongylus brasiliensis infection impairs worm expulsion and recall of protective memory CD4⁺ T cell responses.
由: Hlumani Ndlovu, et al.
出版: (2014-02-01)

Negative Association of Interleukin-33 Plasma Levels and Schistosomiasis Infection in a Site of Polyparasitism in Rural Cameroon
由: Severin Donald Kamdem, et al.
出版: (2019-12-01)

Diagnostic, prognostic, and therapeutic potentials of gut microbiome profiling in human schistosomiasis: A comprehensive systematic review.
由: Martin Gael Oyono, et al.
出版: (2025-02-01)

Interleukin-4 Receptor Alpha: From Innate to Adaptive Immunity in Murine Models of Cutaneous Leishmaniasis
由: Ramona Hurdayal, et al.
出版: (2017-11-01)

Reduced plasma levels of GM-CSF is a common feature of Schistosoma mansoni-infected school-aged children
由: Severin Donald Kamdem, et al.
出版: (2025-02-01)

Combined analysis of host IFN-γ, IL-2 and IP-10 as potential LTBI biomarkers in ESAT-6/CFP-10 stimulated blood
由: Antony M. Rapulana, et al.
出版: (2024-01-01)

Signaling C-type lectin receptors in antimycobacterial immunity.
由: Mohlopheni J Marakalala, et al.
出版: (2017-06-01)

Granulomas and inflammation: Host-Directed Therapies for Tuberculosis
由: Hlumani Ndlovu, et al.
出版: (2016-10-01)

Excretory/secretory-products of Echinococcus multilocularis larvae induce apoptosis and tolerogenic properties in dendritic cells in vitro.
由: Justin Komguep Nono, et al.
出版: (2012-01-01)

Generation of Multicellular 3D Liver Organoids From Induced Pluripotent Stem Cells as a Tool for Modelling Liver Diseases
由: Setjie Maepa, et al.
出版: (2024-08-01)

Interleukin-6 is crucial for recall of influenza-specific memory CD4 T cells.
由: Maria Paula Longhi, et al.
出版: (2008-02-01)

Coping with drought: Reflection of communal cattle farmers in Umzingwane district in Zimbabwe
由: Thabo Ndlovu
出版: (2019-10-01)

Are cash transfers the panacea to local involvement in humanitarian decision-making? Evidence from World Vision projects in Umzingwane
由: Thabo Ndlovu, et al.
出版: (2019-02-01)

A clinical case of adult-onset Still's disease resistant to therapy with tumor necrosis factor-alpha inhibitors and interleukin-6 inhibitors
由: R. R. Samigullina, et al.
出版: (2019-03-01)

Neural response to sad autobiographical recall and sad music listening post recall reveals distinct brain activation in alpha and gamma bands.
由: Ashish Gupta, et al.
出版: (2023-01-01)

Neural response to sad autobiographical recall and sad music listening post recall reveals distinct brain activation in alpha and gamma bands
由: Ashish Gupta, et al.
出版: (2023-01-01)

Maintenance and recall of memory T cell populations against tuberculosis: Implications for vaccine design
由: Xin Liu, et al.
出版: (2023-03-01)

Moderate regular physical exercise can help in alleviating the systemic impact of schistosomiasis infection on brain cognitive function
由: Inssaf Berkiks, et al.
出版: (2025-01-01)

Anti-Interleukin-1 Agents in Adult Onset Still's Disease
由: Cecilia Giampietro, et al.
出版: (2012-01-01)

The Host Peritoneal Cavity Harbors Prominent Memory Th2 and Early Recall Responses to an Intestinal Nematode
由: Ivet A. Yordanova, et al.
出版: (2022-03-01)

Pancreatic, but not myeloid-cell, expression of interleukin-1alpha is required for maintenance of insulin secretion and whole body glucose homeostasis
由: J. Jason Collier, et al.
出版: (2021-02-01)

Environmental and microbial factors influence affective and cognitive behavior in C57BL/6 sub-strains
由: Nada Abdel Aziz, et al.
出版: (2023-04-01)

T helper1/T helper2 cells and resistance/susceptibility to Leishmania infection: is this paradigm still relevant?
由: James eAlexander, et al.
出版: (2012-04-01)

Alpha reactivity to first names differs in subjects with high and low dream recall frequency
由: Perrine Marie RUBY, et al.
出版: (2013-08-01)

Establishment and maintenance of DNA methylation in nematode feeding sites
由: Morgan Bennett, et al.
出版: (2023-01-01)

Maintenance Therapy With Interleukin-2 for Childhood AML
由: Arnaud Petit, et al.
出版: (2018-12-01)

Validation of proteins associated with pathological damage in human tuberculosis granulomas: study protocol [version 1; peer review: 2 approved]
由: Jessica More, et al.
出版: (2023-03-01)

Community-based participatory planning contribution to social capital for enhanced disaster resilience in rural Matobo, Zimbabwe
由: Thabo Ndlovu, et al.
出版: (2023-11-01)

Mycobacterial FtsEX-RipC interaction is required for normal growth and cell morphology in rifampicin and low ionic strength conditions
由: Veneshley Samuels, et al.
出版: (2024-03-01)

Dectin-1-Syk-CARD9 Signaling Pathway in TB Immunity
由: Matthew Wagener, et al.
出版: (2018-02-01)

How do selective attentional processes contribute to maintenance and recall in children’s working memory capacity?
由: Hannah Elizabeth Roome, et al.
出版: (2014-12-01)

Neuroprotective Effect of Vinpocetine against Lead Acetate-Instigated Neurotoxicity in Rats by Evaluation Tumor Necrosis Factor-Alpha, Interleukin-1Beta and Interleukin-10
由: Manal Abdulkhaliq Ibrahim, et al.
出版: (2022-12-01)

Production of Recombinant Alpha-Synuclein: Still No Standardized Protocol in Sight
由: Mohammed Al-Azzani, et al.
出版: (2022-02-01)