Interleukin-4 receptor alpha is still required after Th2 polarization for the maintenance and the recall of protective immunity to Nematode infection.

There is currently no vaccine against parasitic nematodes and the knowledge on the mechanisms by which protective immunity against this class of parasites is achieved is continuously expanding. Nematode parasites trigger a host protective type 2 immune response via interleukin-4 receptor alpha (IL-4...

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Autori principali: Justin Komguep Nono, Hlumani Ndlovu, Nada Abdel Aziz, Thabo Mpotje, Lerato Hlaka, Frank Brombacher
Natura: Articolo
Lingua:English
Pubblicazione: Public Library of Science (PLoS) 2017-06-01
Serie:PLoS Neglected Tropical Diseases
Accesso online:http://europepmc.org/articles/PMC5501681?pdf=render