Role of CD45 signaling pathway in galactoxylomannan-induced T cell damage.

Role of CD45 signaling pathway in galactoxylomannan-induced T cell damage.

Previously, we reported that Galactoxylomannan (GalXM) activates the extrinsic and intrinsic apoptotic pathways through an interaction with the glycoreceptors on T cells. In this study we establish the role of the glycoreceptor CD45 in GalXM-induced T cell apoptosis, using CD45(+/+) and CD45(-/-) ce...

Full description

Bibliographic Details
Main Authors: Eva Pericolini, Elena Gabrielli, Giovanni Bistoni, Elio Cenci, Stefano Perito, Siu-Kei Chow, Francesca Riuzzi, Rosario Donato, Arturo Casadevall, Anna Vecchiarelli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2939064?pdf=render

Similar Items

Similar Items