Ligandless Palladium-Catalyzed Direct C-5 Arylation of Azoles Promoted by Benzoic Acid in Anisole

Ligandless Palladium-Catalyzed Direct C-5 Arylation of Azoles Promoted by Benzoic Acid in Anisole

The palladium-catalyzed direct arylation of azoles with (hetero)aryl halides is nowadays one of the most versatile and efficient procedures for the selective synthesis of heterobiaryls. Although this procedure is, due to its characteristics, also of great interest in the industrial field, the wide u...

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Bibliographic Details
Main Authors: Elisabetta Rosadoni, Federico Banchini, Sara Bellini, Marco Lessi, Luca Pasquinelli, Fabio Bellina
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Molecules
Subjects:
azoles
direct arylation
C–C coupling
palladium
aromatic solvents
regioselectivity
Online Access:https://www.mdpi.com/1420-3049/27/23/8454

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