Effect of multimodal exercise training on physical fitness indices, cognitive status, and depressive symptoms in Alzheimer's disease
ABSTRACT. In Alzheimer's disease (AD) patients, low levels of physical fitness (PF) and cognitive status are associated with high rates of depression. However, this condition can be improved through physical training. Objective: The aim of the present study was to investigate the effect of mul...
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| Format: | Article |
| Language: | English |
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Associação Neurologia Cognitiva e do Comportamento
2023-05-01
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| Series: | Dementia & Neuropsychologia |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642023000100305&lng=en&tlng=en |
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| author | Amir Hossein Haghighi Masoud Barzoei Seyed Alireza Hosseini Kakhak Francesco Budini Hadi Shahrabadi |
| author_facet | Amir Hossein Haghighi Masoud Barzoei Seyed Alireza Hosseini Kakhak Francesco Budini Hadi Shahrabadi |
| author_sort | Amir Hossein Haghighi |
| collection | DOAJ |
| description | ABSTRACT. In Alzheimer's disease (AD) patients, low levels of physical fitness (PF) and cognitive status are associated with high rates of depression. However, this condition can be improved through physical training. Objective: The aim of the present study was to investigate the effect of multimodal exercise training (MET) on aerobic endurance, muscular strength, agility, dynamic balance, cognitive status, and depressive symptoms in men with mild-to-moderate AD. Methods: A total of 25 elderly men with a diagnosis of mild-to-moderate AD were randomly categorized into an MET or a control group. The subjects in the MET group participated in a 12-week, three sessions per week MET program that included resistance, balance, and aerobic exercises. While the participants in the control group did not perform any regular exercise training during this period. Patients’ cognitive status and depressive symptoms were assessed by Mini-Mental State Examination and the Geriatric Depression Scale-15 (GDS-15) questionnaires. PF indicators such as aerobic endurance, muscular strength, agility, and dynamic balance, as well as cognitive status and depressive symptoms, were taken from all the subjects before and after MET. Results: The participants in the MET group improved handgrip, upper and lower body strength, agility, dynamic balance, and depressive symptoms (p<0.05). The intervention had no significant effect on aerobic endurance and cognitive status (p>0.05). Conclusions: MET is an effective strategy to improve muscular strength, agility, dynamic balance, and depressive symptoms in men with mild-to-moderate AD. It is recommended for AD patients to engage in this type of exercise to reduce AD complications. |
| first_indexed | 2024-03-13T08:44:25Z |
| format | Article |
| id | doaj.art-bf18b68d8b6840aebcbb88468a5c5004 |
| institution | Directory Open Access Journal |
| issn | 1980-5764 |
| language | English |
| last_indexed | 2024-03-13T08:44:25Z |
| publishDate | 2023-05-01 |
| publisher | Associação Neurologia Cognitiva e do Comportamento |
| record_format | Article |
| series | Dementia & Neuropsychologia |
| spelling | doaj.art-bf18b68d8b6840aebcbb88468a5c50042023-05-30T07:36:26ZengAssociação Neurologia Cognitiva e do ComportamentoDementia & Neuropsychologia1980-57642023-05-011710.1590/1980-5764-dn-2022-0008Effect of multimodal exercise training on physical fitness indices, cognitive status, and depressive symptoms in Alzheimer's diseaseAmir Hossein Haghighihttps://orcid.org/0000-0002-7258-9737Masoud Barzoeihttps://orcid.org/0000-0002-7534-9499Seyed Alireza Hosseini Kakhakhttps://orcid.org/0000-0002-7510-2445Francesco Budinihttps://orcid.org/0000-0002-1729-3853Hadi Shahrabadihttps://orcid.org/0000-0001-8404-6927ABSTRACT. In Alzheimer's disease (AD) patients, low levels of physical fitness (PF) and cognitive status are associated with high rates of depression. However, this condition can be improved through physical training. Objective: The aim of the present study was to investigate the effect of multimodal exercise training (MET) on aerobic endurance, muscular strength, agility, dynamic balance, cognitive status, and depressive symptoms in men with mild-to-moderate AD. Methods: A total of 25 elderly men with a diagnosis of mild-to-moderate AD were randomly categorized into an MET or a control group. The subjects in the MET group participated in a 12-week, three sessions per week MET program that included resistance, balance, and aerobic exercises. While the participants in the control group did not perform any regular exercise training during this period. Patients’ cognitive status and depressive symptoms were assessed by Mini-Mental State Examination and the Geriatric Depression Scale-15 (GDS-15) questionnaires. PF indicators such as aerobic endurance, muscular strength, agility, and dynamic balance, as well as cognitive status and depressive symptoms, were taken from all the subjects before and after MET. Results: The participants in the MET group improved handgrip, upper and lower body strength, agility, dynamic balance, and depressive symptoms (p<0.05). The intervention had no significant effect on aerobic endurance and cognitive status (p>0.05). Conclusions: MET is an effective strategy to improve muscular strength, agility, dynamic balance, and depressive symptoms in men with mild-to-moderate AD. It is recommended for AD patients to engage in this type of exercise to reduce AD complications.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642023000100305&lng=en&tlng=enExercisePhysical FitnessDepressionAlzheimer Disease |
| spellingShingle | Amir Hossein Haghighi Masoud Barzoei Seyed Alireza Hosseini Kakhak Francesco Budini Hadi Shahrabadi Effect of multimodal exercise training on physical fitness indices, cognitive status, and depressive symptoms in Alzheimer's disease Dementia & Neuropsychologia Exercise Physical Fitness Depression Alzheimer Disease |
| title | Effect of multimodal exercise training on physical fitness indices, cognitive status, and depressive symptoms in Alzheimer's disease |
| title_full | Effect of multimodal exercise training on physical fitness indices, cognitive status, and depressive symptoms in Alzheimer's disease |
| title_fullStr | Effect of multimodal exercise training on physical fitness indices, cognitive status, and depressive symptoms in Alzheimer's disease |
| title_full_unstemmed | Effect of multimodal exercise training on physical fitness indices, cognitive status, and depressive symptoms in Alzheimer's disease |
| title_short | Effect of multimodal exercise training on physical fitness indices, cognitive status, and depressive symptoms in Alzheimer's disease |
| title_sort | effect of multimodal exercise training on physical fitness indices cognitive status and depressive symptoms in alzheimer s disease |
| topic | Exercise Physical Fitness Depression Alzheimer Disease |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642023000100305&lng=en&tlng=en |
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