An interesting case of chronic myeloid leukemia (CML) with T315I mutation raising suspicion of de novo AML, a diagnostic conundrum

Abstract Chronic myeloid leukemia (CML) is a myeloproliferative disorder due to translocation between chromosomes (9, 22), known as the “Philadelphia chromosome.” In 2016, the World health organization (WHO) introduced a new clinical entity of de novo acute myeloid leukemia (AML). Both diseases shar...

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Main Authors: Phool Iqbal, Aamir Shahzad, Zubair Shahid, Firdous Ghori, Halima Elomri, Dina Soliman
Format: Article
Language:English
Published: Wiley 2023-05-01
Series:Clinical Case Reports
Subjects:
Online Access:https://doi.org/10.1002/ccr3.5908
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author Phool Iqbal
Aamir Shahzad
Zubair Shahid
Firdous Ghori
Halima Elomri
Dina Soliman
author_facet Phool Iqbal
Aamir Shahzad
Zubair Shahid
Firdous Ghori
Halima Elomri
Dina Soliman
author_sort Phool Iqbal
collection DOAJ
description Abstract Chronic myeloid leukemia (CML) is a myeloproliferative disorder due to translocation between chromosomes (9, 22), known as the “Philadelphia chromosome.” In 2016, the World health organization (WHO) introduced a new clinical entity of de novo acute myeloid leukemia (AML). Both diseases share some commonalities, therefore, create a challenge to diagnose.
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spelling doaj.art-bf192578f19543cf8e36f77de4ee2f202023-05-25T05:58:40ZengWileyClinical Case Reports2050-09042023-05-01115n/an/a10.1002/ccr3.5908An interesting case of chronic myeloid leukemia (CML) with T315I mutation raising suspicion of de novo AML, a diagnostic conundrumPhool Iqbal0Aamir Shahzad1Zubair Shahid2Firdous Ghori3Halima Elomri4Dina Soliman5Department of Internal Medicine and Medicine Critical Care Department Hamad Medical Corporation Doha QatarDepartment of Internal Medicine Readings Hospital Tower Health Reading Pennsylvania USADepartment of Internal Medicine and Cardiology Hamad Medical Corporation Doha QatarMedical Oncology‐Hematology Department National Centre for Cancer Care and Research (NCCCR) Hamad Medical Corporation (HMC) Doha QatarMedical Oncology‐Hematology Department National Centre for Cancer Care and Research (NCCCR) Hamad Medical Corporation (HMC) Doha QatarMedical Oncology‐Hematology Department National Centre for Cancer Care and Research (NCCCR) Hamad Medical Corporation (HMC) Doha QatarAbstract Chronic myeloid leukemia (CML) is a myeloproliferative disorder due to translocation between chromosomes (9, 22), known as the “Philadelphia chromosome.” In 2016, the World health organization (WHO) introduced a new clinical entity of de novo acute myeloid leukemia (AML). Both diseases share some commonalities, therefore, create a challenge to diagnose.https://doi.org/10.1002/ccr3.5908BCR‐ABL1+ AMLchronic myeloid leukemiade Novo AMLPhiladelphia chromosomeT315I
spellingShingle Phool Iqbal
Aamir Shahzad
Zubair Shahid
Firdous Ghori
Halima Elomri
Dina Soliman
An interesting case of chronic myeloid leukemia (CML) with T315I mutation raising suspicion of de novo AML, a diagnostic conundrum
Clinical Case Reports
BCR‐ABL1+ AML
chronic myeloid leukemia
de Novo AML
Philadelphia chromosome
T315I
title An interesting case of chronic myeloid leukemia (CML) with T315I mutation raising suspicion of de novo AML, a diagnostic conundrum
title_full An interesting case of chronic myeloid leukemia (CML) with T315I mutation raising suspicion of de novo AML, a diagnostic conundrum
title_fullStr An interesting case of chronic myeloid leukemia (CML) with T315I mutation raising suspicion of de novo AML, a diagnostic conundrum
title_full_unstemmed An interesting case of chronic myeloid leukemia (CML) with T315I mutation raising suspicion of de novo AML, a diagnostic conundrum
title_short An interesting case of chronic myeloid leukemia (CML) with T315I mutation raising suspicion of de novo AML, a diagnostic conundrum
title_sort interesting case of chronic myeloid leukemia cml with t315i mutation raising suspicion of de novo aml a diagnostic conundrum
topic BCR‐ABL1+ AML
chronic myeloid leukemia
de Novo AML
Philadelphia chromosome
T315I
url https://doi.org/10.1002/ccr3.5908
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