Evaluation of Cellular Response to the Indigenously Fabricated Dental Magnet for Application in Prosthodontics- An Animal Study
Introduction: Prosthetic constructions retained by magnets play an important role in the application of dental removable prosthesis and orofacial epithesis. One of the issues during the introduction of these magnets into clinical practice is that they may exert some negative impact on the surrou...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2017-11-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/10899/29287_281117_29287_CE(Ra1)_F(SS)_PF1(AA_PK_GG)_PFA(MJ_GG).pdf |
| Summary: | Introduction: Prosthetic constructions retained by magnets
play an important role in the application of dental removable
prosthesis and orofacial epithesis. One of the issues during the
introduction of these magnets into clinical practice is that they
may exert some negative impact on the surrounding tissues.
Therefore, the effect of the indigenous dental magnets on the
cellular changes needs to be qualitatively evaluated.
Aim: To check the effect of indigenously fabricated dental
magnets on the cellular changes in the dermis and epidermis
of rabbits.
Materials and Methods: A total of five New Zealand rabbits were
selected from the animal house of SDM Medical College, Dharwad.
A small sub cutaneous incision was made on the back region of the
rabbit on right and left side with a no. 15 Bard Parker (BP) blade
under phenobarbitone anaesthesia. The skin layers were slightly
dissected under the incision creating a pouch. Bare magnet without
casing (control) was embedded in the pouch on one side and
the teflon encased magnet (test) on the other side. Sutures were
placed and post-operative care was taken. The obtained tissues
were paraffinized and sections were stained with haematoxylin and
eosin. The parameters assessed were thickness and keratinization
of epidermis and arrangement of fibres and type of infalmatory cells
in dermis. Data was subjected to statistical analysis. Mann-Whitney
U test was performed.
Results: Statistically significant difference was observed in
keratinization at 28 days and was still observed after 3 months.
There was no difference in dermal fibres arrangement or chronic
inflammation at the end of three months between the two
groups.
Haematoxylin and eosin stained sections from control and
test showed mild chronic inflammatory response at 28 days.
Inflammation subsided in three months in the test sample,
whereas focal aggregates of inflammation were evident in
control sections. Persistence of inflammatory cell reaction
in control samples indicates mild cell toxicity induced by the
magnet.
Conclusion: To conclude indigenously fabricated dental magnet
did not show host inflammatory reaction in the animal study
model over the control magnet. |
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| ISSN: | 2249-782X 0973-709X |