MEG measured delta waves increase in adolescents after concussion
Abstract Introduction The purpose of this study is to determine if delta waves, measured by magnetoencephalography (MEG), increase in adolescents due to a sports concussion. Methods Twenty‐four adolescents (age 14–17) completed pre‐ and postseason MRI and MEG scanning. MEG whole‐brain delta power wa...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2022-09-01
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| Series: | Brain and Behavior |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/brb3.2720 |
| _version_ | 1798033512819851264 |
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| author | Elizabeth M. Davenport Jillian E. Urban Christopher Vaughan Jesse C. DeSimone Ben Wagner Mark A. Espeland Alexander K. Powers Christopher T. Whitlow Joel D. Stitzel Joseph A. Maldjian |
| author_facet | Elizabeth M. Davenport Jillian E. Urban Christopher Vaughan Jesse C. DeSimone Ben Wagner Mark A. Espeland Alexander K. Powers Christopher T. Whitlow Joel D. Stitzel Joseph A. Maldjian |
| author_sort | Elizabeth M. Davenport |
| collection | DOAJ |
| description | Abstract Introduction The purpose of this study is to determine if delta waves, measured by magnetoencephalography (MEG), increase in adolescents due to a sports concussion. Methods Twenty‐four adolescents (age 14–17) completed pre‐ and postseason MRI and MEG scanning. MEG whole‐brain delta power was calculated for each subject and normalized by the subject's total power. In eight high school football players diagnosed with a concussion during the season (mean age = 15.8), preseason delta power was subtracted from their postseason scan. In eight high school football players without a concussion (mean age = 15.7), preseason delta power was subtracted from postseason delta power and in eight age‐matched noncontact controls (mean age = 15.9), baseline delta power was subtracted from a 4‐month follow‐up scan. ANOVA was used to compare the mean differences between preseason and postseason scans for the three groups of players, with pairwise comparisons based on Student's t‐test method. Results Players with concussions had significantly increased delta wave power at their postseason scans than nonconcussed players (p = .018) and controls (p = .027). Conclusion We demonstrate that a single concussion during the season in adolescent subjects can increase MEG measured delta frequency power at their postseason scan. This adds to the growing body of literature indicating increased delta power following a concussion. |
| first_indexed | 2024-04-11T20:31:56Z |
| format | Article |
| id | doaj.art-bf1e6c497f5840fdacf77e52428ff693 |
| institution | Directory Open Access Journal |
| issn | 2162-3279 |
| language | English |
| last_indexed | 2024-04-11T20:31:56Z |
| publishDate | 2022-09-01 |
| publisher | Wiley |
| record_format | Article |
| series | Brain and Behavior |
| spelling | doaj.art-bf1e6c497f5840fdacf77e52428ff6932022-12-22T04:04:29ZengWileyBrain and Behavior2162-32792022-09-01129n/an/a10.1002/brb3.2720MEG measured delta waves increase in adolescents after concussionElizabeth M. Davenport0Jillian E. Urban1Christopher Vaughan2Jesse C. DeSimone3Ben Wagner4Mark A. Espeland5Alexander K. Powers6Christopher T. Whitlow7Joel D. Stitzel8Joseph A. Maldjian9Advanced Neuroscience Imaging Research (ANSIR) Laboratory University of Texas Southwestern Medical Center Dallas TexasDepartment of Biomedical Engineering Wake Forest School of Medicine Winston‐Salem North CarolinaDepartment of Neurosurgery Wake Forest School of Medicine Winston‐Salem North CarolinaAdvanced Neuroscience Imaging Research (ANSIR) Laboratory University of Texas Southwestern Medical Center Dallas TexasAdvanced Neuroscience Imaging Research (ANSIR) Laboratory University of Texas Southwestern Medical Center Dallas TexasDepartment of Radiology‐Neuroradiology Wake Forest School of Medicine Winston‐Salem North CarolinaClinical and Translational Science Institute Wake Forest School of Medicine Winston‐Salem North CarolinaDepartment of Biomedical Engineering Wake Forest School of Medicine Winston‐Salem North CarolinaDepartment of Biomedical Engineering Wake Forest School of Medicine Winston‐Salem North CarolinaAdvanced Neuroscience Imaging Research (ANSIR) Laboratory University of Texas Southwestern Medical Center Dallas TexasAbstract Introduction The purpose of this study is to determine if delta waves, measured by magnetoencephalography (MEG), increase in adolescents due to a sports concussion. Methods Twenty‐four adolescents (age 14–17) completed pre‐ and postseason MRI and MEG scanning. MEG whole‐brain delta power was calculated for each subject and normalized by the subject's total power. In eight high school football players diagnosed with a concussion during the season (mean age = 15.8), preseason delta power was subtracted from their postseason scan. In eight high school football players without a concussion (mean age = 15.7), preseason delta power was subtracted from postseason delta power and in eight age‐matched noncontact controls (mean age = 15.9), baseline delta power was subtracted from a 4‐month follow‐up scan. ANOVA was used to compare the mean differences between preseason and postseason scans for the three groups of players, with pairwise comparisons based on Student's t‐test method. Results Players with concussions had significantly increased delta wave power at their postseason scans than nonconcussed players (p = .018) and controls (p = .027). Conclusion We demonstrate that a single concussion during the season in adolescent subjects can increase MEG measured delta frequency power at their postseason scan. This adds to the growing body of literature indicating increased delta power following a concussion.https://doi.org/10.1002/brb3.2720concussiondelta wavesfootballmagnetoencephalography (MEG) |
| spellingShingle | Elizabeth M. Davenport Jillian E. Urban Christopher Vaughan Jesse C. DeSimone Ben Wagner Mark A. Espeland Alexander K. Powers Christopher T. Whitlow Joel D. Stitzel Joseph A. Maldjian MEG measured delta waves increase in adolescents after concussion Brain and Behavior concussion delta waves football magnetoencephalography (MEG) |
| title | MEG measured delta waves increase in adolescents after concussion |
| title_full | MEG measured delta waves increase in adolescents after concussion |
| title_fullStr | MEG measured delta waves increase in adolescents after concussion |
| title_full_unstemmed | MEG measured delta waves increase in adolescents after concussion |
| title_short | MEG measured delta waves increase in adolescents after concussion |
| title_sort | meg measured delta waves increase in adolescents after concussion |
| topic | concussion delta waves football magnetoencephalography (MEG) |
| url | https://doi.org/10.1002/brb3.2720 |
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