Cardiac Fibrosis: Cellular Effectors, Molecular Pathways, and Exosomal Roles
Cardiac fibrosis, a common pathophysiologic process in most heart diseases, refers to an excess of extracellular matrix (ECM) deposition by cardiac fibroblasts (CFs), which can lead to cardiac dysfunction and heart failure subsequently. Not only CFs but also several other cell types including macrop...
Main Authors: | Wenyang Jiang, Yuyan Xiong, Xiaosong Li, Yuejin Yang |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-08-01
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Series: | Frontiers in Cardiovascular Medicine |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fcvm.2021.715258/full |
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