Trends and associated factors of HIV, HCV and syphilis infection among different drug users in the China–Vietnam border area: an 11-year cross-sectional study (2010–2020)
Abstract Background Data on recent human immunodeficiency virus (HIV), hepatitis C virus (HCV) and syphilis prevalence among drug users in the Southwest China are sparse despite the high burden of drug use. This study aims at assessing the prevalence trends and related factors of HIV, HCV and syphil...
| Main Authors: | , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-09-01
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| Series: | BMC Infectious Diseases |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12879-023-08239-3 |
| _version_ | 1797453765216829440 |
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| author | Tong Luo Zhaosen Lin Zhenxian Wu Ping Cen Aidan Nong Rongye Huang Jianhua Che Fengfeng Liang Yuan Yang Jie Liu Li Huang Jie Cai Yanyun Ou Li Ye Lijuan Bao Bingyu Liang Hao Liang |
| author_facet | Tong Luo Zhaosen Lin Zhenxian Wu Ping Cen Aidan Nong Rongye Huang Jianhua Che Fengfeng Liang Yuan Yang Jie Liu Li Huang Jie Cai Yanyun Ou Li Ye Lijuan Bao Bingyu Liang Hao Liang |
| author_sort | Tong Luo |
| collection | DOAJ |
| description | Abstract Background Data on recent human immunodeficiency virus (HIV), hepatitis C virus (HCV) and syphilis prevalence among drug users in the Southwest China are sparse despite the high burden of drug use. This study aims at assessing the prevalence trends and related factors of HIV, HCV and syphilis infection among different drug users in the China–Vietnam border area. Methods A continuous cross-sectional survey was conducted among drug users from 2010 to 2020 in the China–Vietnam border area. Chi-square trend tests were used to assess the trend of HIV, HCV and syphilis prevalence and the proportion for drug type used by drug users. Multivariate logistic regression was used to identify associated factors of HIV, HCV and syphilis infection in different drug users. Results In this study, a total of 28,951 drug users were included, of which 27,893 (96.45%) male, 15,660 (54.09%) aged 13–34 years, 24,543 (84.77%) heroin-only users, 2062 (7.12%) synthetic drug-only (SD-only) users and 2346 (8.10%) poly-drug users. From 2010 to 2020, the proportion of heroin-only users decreased from 87.79% to 75.46%, whereas SD-only users and poly-drug users increased from 5.16% to 16.03%, and from 7.05% to 8.52%, respectively. The prevalence of HIV, HCV, and syphilis during the study period declined from 12.76%, 60.37% and 5.72% to 4.35%, 53.29% and 4.53%, respectively, among heroin-only users and declined from 18.30%, 66.67% and 15.69% to 6.95%, 27.81% and 5.35%, respectively, among poly-drug users; however, the prevalence of HIV and HCV among SD-only users increased from 0.89% and 8.93% to 2.84% and 18.75%, respectively. Having ever injected drugs and needle sharing were common associated factors for both HIV and HCV infection among poly-drug users and heroin-only users. Aged ≥ 35 years old was an associated factor for HIV, HCV and syphilis infection among the SD-only users. Female drug users were at high risk of contracting syphilis among three different drug users. Conclusions The prevalence of HIV, HCV and syphilis among heroin-only users and poly-drug users decreased during the study period. However, the prevalence of HIV and HCV among SD-only users increased. Comprehensive intervention strategies, particularly focusing on the SD-only users are needed in order to bring down the disease burden in this population in the China–Vietnam border areas. |
| first_indexed | 2024-03-09T15:27:35Z |
| format | Article |
| id | doaj.art-bf1f5667ac8f496fb6ec3d4a869ae93a |
| institution | Directory Open Access Journal |
| issn | 1471-2334 |
| language | English |
| last_indexed | 2024-03-09T15:27:35Z |
| publishDate | 2023-09-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Infectious Diseases |
| spelling | doaj.art-bf1f5667ac8f496fb6ec3d4a869ae93a2023-11-26T12:28:16ZengBMCBMC Infectious Diseases1471-23342023-09-0123111110.1186/s12879-023-08239-3Trends and associated factors of HIV, HCV and syphilis infection among different drug users in the China–Vietnam border area: an 11-year cross-sectional study (2010–2020)Tong Luo0Zhaosen Lin1Zhenxian Wu2Ping Cen3Aidan Nong4Rongye Huang5Jianhua Che6Fengfeng Liang7Yuan Yang8Jie Liu9Li Huang10Jie Cai11Yanyun Ou12Li Ye13Lijuan Bao14Bingyu Liang15Hao Liang16Guangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical UniversityQinzhou Center for Disease Control and PreventionChongzuo Center for Disease Control and PreventionGuangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical UniversityChongzuo Center for Disease Control and PreventionQinzhou Center for Disease Control and PreventionChongzuo Center for Disease Control and PreventionQinzhou Center for Disease Control and PreventionCollaborative Innovation Centre of Regenerative Medicine and Medical Bioresource Development and Application Co-constructed by the Province and Ministry, Life Science Institute, Guangxi Medical UniversityGuangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical UniversityChongzuo Center for Disease Control and PreventionChongzuo Center for Disease Control and PreventionChongzuo Center for Disease Control and PreventionGuangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical UniversityChongzuo Center for Disease Control and PreventionGuangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical UniversityGuangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical UniversityAbstract Background Data on recent human immunodeficiency virus (HIV), hepatitis C virus (HCV) and syphilis prevalence among drug users in the Southwest China are sparse despite the high burden of drug use. This study aims at assessing the prevalence trends and related factors of HIV, HCV and syphilis infection among different drug users in the China–Vietnam border area. Methods A continuous cross-sectional survey was conducted among drug users from 2010 to 2020 in the China–Vietnam border area. Chi-square trend tests were used to assess the trend of HIV, HCV and syphilis prevalence and the proportion for drug type used by drug users. Multivariate logistic regression was used to identify associated factors of HIV, HCV and syphilis infection in different drug users. Results In this study, a total of 28,951 drug users were included, of which 27,893 (96.45%) male, 15,660 (54.09%) aged 13–34 years, 24,543 (84.77%) heroin-only users, 2062 (7.12%) synthetic drug-only (SD-only) users and 2346 (8.10%) poly-drug users. From 2010 to 2020, the proportion of heroin-only users decreased from 87.79% to 75.46%, whereas SD-only users and poly-drug users increased from 5.16% to 16.03%, and from 7.05% to 8.52%, respectively. The prevalence of HIV, HCV, and syphilis during the study period declined from 12.76%, 60.37% and 5.72% to 4.35%, 53.29% and 4.53%, respectively, among heroin-only users and declined from 18.30%, 66.67% and 15.69% to 6.95%, 27.81% and 5.35%, respectively, among poly-drug users; however, the prevalence of HIV and HCV among SD-only users increased from 0.89% and 8.93% to 2.84% and 18.75%, respectively. Having ever injected drugs and needle sharing were common associated factors for both HIV and HCV infection among poly-drug users and heroin-only users. Aged ≥ 35 years old was an associated factor for HIV, HCV and syphilis infection among the SD-only users. Female drug users were at high risk of contracting syphilis among three different drug users. Conclusions The prevalence of HIV, HCV and syphilis among heroin-only users and poly-drug users decreased during the study period. However, the prevalence of HIV and HCV among SD-only users increased. Comprehensive intervention strategies, particularly focusing on the SD-only users are needed in order to bring down the disease burden in this population in the China–Vietnam border areas.https://doi.org/10.1186/s12879-023-08239-3HIVHCVSyphilisChina–Vietnam borderDrug users |
| spellingShingle | Tong Luo Zhaosen Lin Zhenxian Wu Ping Cen Aidan Nong Rongye Huang Jianhua Che Fengfeng Liang Yuan Yang Jie Liu Li Huang Jie Cai Yanyun Ou Li Ye Lijuan Bao Bingyu Liang Hao Liang Trends and associated factors of HIV, HCV and syphilis infection among different drug users in the China–Vietnam border area: an 11-year cross-sectional study (2010–2020) BMC Infectious Diseases HIV HCV Syphilis China–Vietnam border Drug users |
| title | Trends and associated factors of HIV, HCV and syphilis infection among different drug users in the China–Vietnam border area: an 11-year cross-sectional study (2010–2020) |
| title_full | Trends and associated factors of HIV, HCV and syphilis infection among different drug users in the China–Vietnam border area: an 11-year cross-sectional study (2010–2020) |
| title_fullStr | Trends and associated factors of HIV, HCV and syphilis infection among different drug users in the China–Vietnam border area: an 11-year cross-sectional study (2010–2020) |
| title_full_unstemmed | Trends and associated factors of HIV, HCV and syphilis infection among different drug users in the China–Vietnam border area: an 11-year cross-sectional study (2010–2020) |
| title_short | Trends and associated factors of HIV, HCV and syphilis infection among different drug users in the China–Vietnam border area: an 11-year cross-sectional study (2010–2020) |
| title_sort | trends and associated factors of hiv hcv and syphilis infection among different drug users in the china vietnam border area an 11 year cross sectional study 2010 2020 |
| topic | HIV HCV Syphilis China–Vietnam border Drug users |
| url | https://doi.org/10.1186/s12879-023-08239-3 |
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