A pathogenic germline BRCA2 variant in a patient with hypopharyngeal squamous cell carcinoma

Abstract Pathogenic germline BRCA2 variants may be associated with an increased risk of hypopharyngeal squamous cell carcinoma that is more responsive to chemoradiation and chemotherapeutics targeting defective double‐strand DNA repair.

Bibliographic Details
Main Authors: Tatiana Correa, Douglas E. Laux, Henry T. Hoffman
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Clinical Case Reports
Subjects:
Online Access:https://doi.org/10.1002/ccr3.3548
Description
Summary:Abstract Pathogenic germline BRCA2 variants may be associated with an increased risk of hypopharyngeal squamous cell carcinoma that is more responsive to chemoradiation and chemotherapeutics targeting defective double‐strand DNA repair.
ISSN:2050-0904