Effects of onopordia, a novel isolated compound from Onopordon acanthium, on pentylenetetrazole-induced seizures in mice: Possible involvement of nitric oxide pathway

Effects of onopordia, a novel isolated compound from Onopordon acanthium, on pentylenetetrazole-induced seizures in mice: Possible involvement of nitric oxide pathway

Epilepsy is identified as a brain disorder and characterized by unpredictable disruption of normal brain function. Due to adverse side effect associated with antiepileptic drugs and also resistance profile, improvement of antiepileptic medications with more beneficial anticonvulsant activity is esse...

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Bibliographic Details
Main Authors:	Malihe Hassanzadeh, Niusha Sharifi, Shabnam Mahernia, Nastaran Rahimi, Ahmad Reza Dehpour, Massoud Amanlou
Format:	Article
Language:	English
Published:	Elsevier 2021-01-01
Series:	Journal of Traditional and Complementary Medicine
Subjects:	Onopordon acanthium Nitric oxide Nitric oxide synthase inhibitors Pentylenetetrazole Seizure Mice
Online Access:	http://www.sciencedirect.com/science/article/pii/S2225411018309003

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