| Summary: |
Background:
Propofol alone produces effective anesthesia, but several respiratory and cardiovascular complications are observed with it. Propofol, along with ketamine, is known to reduce the side effects and produce a longer duration of anesthesia. This study aims to compare the efficiency of propofol alone and propofol and ketamine in combination for producing ambulatory anesthesia.
Method:
An observational comparative study was conducted prospectively. 100 patients participated in the study. They were divided into two groups. Group A was given propofol alone, and Group B was given propofol along with ketamine. The hemodynamic stability, duration of analgesia, and effectiveness of anesthesia were compared in both groups.
Results:
The average dose of induction for group A was 2 mg, and for group B was 1.6 mg. The average time for recovery from the induction dose for group A was 3 minutes, and for group B was 10 minutes. The average time of analgesia for group A was 9 minutes, and for group B, it was 49 minutes. Group B had improved hemodynamic stability and a longer duration of analgesia.
Conclusion:
From the findings of the study, it can be concluded that the propofol-ketamine combination for anesthetic gives improved hemodynamic stability, effective anesthesia, and a longer duration of analgesia compared to only propofol. The time of recovery from the induction dose was prolonged in the case of the combination compared to propofol alone.
Recommendation:
Propofol with a combination of ketamine produces effective anesthesia with a reduced adverse drug reaction, hence it should be preferred over propofol alone for ambulatory anesthesia.
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