Mitochondrial Oxidative Stress Promotes Cardiac Remodeling in Myocardial Infarction through the Activation of Endoplasmic Reticulum Stress
We have evaluated cardiac function and fibrosis in infarcted male Wistar rats treated with MitoQ (50 mg/kg/day) or vehicle for 4 weeks. A cohort of patients admitted with a first episode of acute MI were also analyzed with cardiac magnetic resonance and T1 mapping during admission and at a 12-month...
Main Authors: | Francisco V. Souza-Neto, Fabian Islas, Sara Jiménez-González, María Luaces, Bunty Ramchandani, Ana Romero-Miranda, Beatriz Delgado-Valero, Elena Roldan-Molina, Melchor Saiz-Pardo, Mª Ángeles Cerón-Nieto, Luis Ortega-Medina, Ernesto Martínez-Martínez, Victoria Cachofeiro |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-06-01
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Series: | Antioxidants |
Subjects: | |
Online Access: | https://www.mdpi.com/2076-3921/11/7/1232 |
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