UK trial of pressurised intraperitoneal aerosolised chemotherapy (PIPAC) with oxaliplatin for colorectal cancer peritoneal metastases (NCT03868228)

This is the first UK trial of pressurised intraperitoneal aerosolised chemotherapy (PIPAC) for colorectal cancer peritoneal metastases. This trial aimed to assess the impact of PIPAC in combination with standard of care systemic treatment on: progression free survival (PFS); quality of life (QoL); a...

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Main Authors: Kyle Peter, Perry Kitrick, Moutadjer Anne, Gilfillan Nicholas, Webb Rosalind, Basak Dolan, Ziprin Paul, Blunt Dominic, Burn James, Van Ree Katherine, Sergot Antoni, Murphy Jamie
Format: Article
Language:English
Published: De Gruyter 2023-09-01
Series:Pleura and Peritoneum
Subjects:
Online Access:https://doi.org/10.1515/pp-2023-0008
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author Kyle Peter
Perry Kitrick
Moutadjer Anne
Gilfillan Nicholas
Webb Rosalind
Basak Dolan
Ziprin Paul
Blunt Dominic
Burn James
Van Ree Katherine
Sergot Antoni
Murphy Jamie
author_facet Kyle Peter
Perry Kitrick
Moutadjer Anne
Gilfillan Nicholas
Webb Rosalind
Basak Dolan
Ziprin Paul
Blunt Dominic
Burn James
Van Ree Katherine
Sergot Antoni
Murphy Jamie
author_sort Kyle Peter
collection DOAJ
description This is the first UK trial of pressurised intraperitoneal aerosolised chemotherapy (PIPAC) for colorectal cancer peritoneal metastases. This trial aimed to assess the impact of PIPAC in combination with standard of care systemic treatment on: progression free survival (PFS); quality of life (QoL); and short-term complications. In addition, this trial set out to demonstrate that PIPAC can be performed safely in operating theatres within a National Health Service (NHS) setting.
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spelling doaj.art-bf2beb63b78e4529ba2e5aa544041e942023-12-26T07:41:08ZengDe GruyterPleura and Peritoneum2364-768X2023-09-018415716510.1515/pp-2023-0008UK trial of pressurised intraperitoneal aerosolised chemotherapy (PIPAC) with oxaliplatin for colorectal cancer peritoneal metastases (NCT03868228)Kyle Peter0Perry Kitrick1Moutadjer Anne2Gilfillan Nicholas3Webb Rosalind4Basak Dolan5Ziprin Paul6Blunt Dominic7Burn James8Van Ree Katherine9Sergot Antoni10Murphy Jamie11Department of Surgery and Cancer, Imperial College London, London, UKImperial College Healthcare NHS Trust, London, UKImperial College Healthcare NHS Trust, London, UKImperial College Healthcare NHS Trust, London, UKImperial College Healthcare NHS Trust, London, UKImperial College Healthcare NHS Trust, London, UKDepartment of Surgery and Cancer, Imperial College London, London, UKImperial College Healthcare NHS Trust, London, UKImperial College Healthcare NHS Trust, London, UKImperial College Healthcare NHS Trust, London, UKImperial College Healthcare NHS Trust, London, UKImperial College London, London, UKThis is the first UK trial of pressurised intraperitoneal aerosolised chemotherapy (PIPAC) for colorectal cancer peritoneal metastases. This trial aimed to assess the impact of PIPAC in combination with standard of care systemic treatment on: progression free survival (PFS); quality of life (QoL); and short-term complications. In addition, this trial set out to demonstrate that PIPAC can be performed safely in operating theatres within a National Health Service (NHS) setting.https://doi.org/10.1515/pp-2023-0008colorectal cancerperitoneal metastasespipacpressurised intraperitoneal aerosolised chemotherapy
spellingShingle Kyle Peter
Perry Kitrick
Moutadjer Anne
Gilfillan Nicholas
Webb Rosalind
Basak Dolan
Ziprin Paul
Blunt Dominic
Burn James
Van Ree Katherine
Sergot Antoni
Murphy Jamie
UK trial of pressurised intraperitoneal aerosolised chemotherapy (PIPAC) with oxaliplatin for colorectal cancer peritoneal metastases (NCT03868228)
Pleura and Peritoneum
colorectal cancer
peritoneal metastases
pipac
pressurised intraperitoneal aerosolised chemotherapy
title UK trial of pressurised intraperitoneal aerosolised chemotherapy (PIPAC) with oxaliplatin for colorectal cancer peritoneal metastases (NCT03868228)
title_full UK trial of pressurised intraperitoneal aerosolised chemotherapy (PIPAC) with oxaliplatin for colorectal cancer peritoneal metastases (NCT03868228)
title_fullStr UK trial of pressurised intraperitoneal aerosolised chemotherapy (PIPAC) with oxaliplatin for colorectal cancer peritoneal metastases (NCT03868228)
title_full_unstemmed UK trial of pressurised intraperitoneal aerosolised chemotherapy (PIPAC) with oxaliplatin for colorectal cancer peritoneal metastases (NCT03868228)
title_short UK trial of pressurised intraperitoneal aerosolised chemotherapy (PIPAC) with oxaliplatin for colorectal cancer peritoneal metastases (NCT03868228)
title_sort uk trial of pressurised intraperitoneal aerosolised chemotherapy pipac with oxaliplatin for colorectal cancer peritoneal metastases nct03868228
topic colorectal cancer
peritoneal metastases
pipac
pressurised intraperitoneal aerosolised chemotherapy
url https://doi.org/10.1515/pp-2023-0008
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