m6A demethylase ALKBH5 is required for antibacterial innate defense by intrinsic motivation of neutrophil migration
Abstract Neutrophil migration into the site of infection is necessary for antibacterial innate defense, whereas impaired neutrophil migration may result in excessive inflammation and even sepsis. The neutrophil migration directed by extracellular signals such as chemokines has been extensively studi...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2022-06-01
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Series: | Signal Transduction and Targeted Therapy |
Online Access: | https://doi.org/10.1038/s41392-022-01020-z |