CEA cell adhesion molecule 5 enriches functional human hematopoietic stem cells capable of long-term multi-lineage engraftment

CEA cell adhesion molecule 5 enriches functional human hematopoietic stem cells capable of long-term multi-lineage engraftment

Summary: Hematopoietic stem cell (HSC) surface markers improve the understanding of cell identity and function. Here, we report that human HSCs can be distinguished by their expression of the CEA Cell Adhesion Molecule 5 (CEACAM5, CD66e), which serves as a marker and a regulator of HSC function. CD6...

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Bibliographic Details
Main Authors: Kuiying Ma, Xuan Wang, Linjie Wu, Lingling Yu, Jinhui Ye, Xueling Li, Lili Geng, Zhongyu Shi, Huihui Yang, Xijuan Zhang, Yongjian Zhang, Shuchang Wu, Pengfei Yuan, Yingchi Zhang, Fang Dong, Sha Hao, Linping Hu, Wensheng Wei, Riguo Fang, Tao Cheng
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:iScience
Subjects:
Cell biology
Stem cells research
Omics
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422302638X

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