Prognostic significance of PD-L1-positive cancer-associated fibroblasts in patients with triple-negative breast cancer

Prognostic significance of PD-L1-positive cancer-associated fibroblasts in patients with triple-negative breast cancer

Abstract Background Cancer-associated fibroblasts (CAFs) are some of the most abundant components of the tumour microenvironment. A recent study suggested that in some cancers, CAFs express programmed death ligand 1 (PD-L1), which can act as a prognostic marker. The aim of this study was to investig...

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Bibliographic Details
Main Authors: Katsuhiro Yoshikawa, Mitsuaki Ishida, Hirotsugu Yanai, Koji Tsuta, Mitsugu Sekimoto, Tomoharu Sugie
Format: Article
Language:English
Published: BMC 2021-03-01
Series:BMC Cancer
Subjects:
Triple-negative breast cancer
Programmed death ligand 1
Cancer-associated fibroblasts
Overall survival
Online Access:https://doi.org/10.1186/s12885-021-07970-x

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