Inhibition of Wnt signaling pathway suppresses radiation-induced dermal fibrosis
Abstract Progressive fibrosis of the dermal tissues is a challenging complication of radiotherapy whose underlying mechanism is not fully understood, and there are few available treatments. The canonical Wnt/β-catenin signaling pathway plays an important role in fibrosis as well as in the epithelial...
Main Authors: | Dong Won Lee, Won Jai Lee, Jaeho Cho, Chae-Ok Yun, Hyun Roh, Hsien Pin Chang, Tai Suk Roh, Ju Hee Lee, Dae Hyun Lew |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2020-08-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-020-70243-3 |
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