Correlation of (1→3)-β-D-glucan with other inflammation markers in chronically HIV infected persons on suppressive antiretroviral therapy
We evaluated associations between levels of BDG and other biomarkers of inflammation in blood from 41 virologically suppressed persons with chronic HIV-infection. We found a significant correlation between BDG and neopterin levels (r=0.68), and trends to significance for correlations with other infl...
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| Format: | Article |
| Language: | English |
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German Medical Science GMS Publishing House
2015-12-01
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| Series: | GMS Infectious Diseases |
| Subjects: | |
| Online Access: | http://www.egms.de/static/en/journals/id/2015-3/id000018.shtml |
| _version_ | 1828768694116810752 |
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| author | Hoenigl, Martin Faria de Oliveira, Michelli Pérez-Santiago, Josué Zhang, Yonglong Woods, Steven Paul Finkelman, Malcolm Gianella, Sara |
| author_facet | Hoenigl, Martin Faria de Oliveira, Michelli Pérez-Santiago, Josué Zhang, Yonglong Woods, Steven Paul Finkelman, Malcolm Gianella, Sara |
| author_sort | Hoenigl, Martin |
| collection | DOAJ |
| description | We evaluated associations between levels of BDG and other biomarkers of inflammation in blood from 41 virologically suppressed persons with chronic HIV-infection. We found a significant correlation between BDG and neopterin levels (r=0.68), and trends to significance for correlations with other inflammation markers (tumor-necrosis-factor-α: r=0.30; interleukin-8: r=0.30; interleukin-6: r=0.28). In conclusion, BDG levels correlated with inflammation markers in a cohort of virologically suppressed individuals with chronic HIV infection. Future studies are needed to evaluate whether BDG may be a marker for morbidity in chronic HIV infection. |
| first_indexed | 2024-12-11T13:34:37Z |
| format | Article |
| id | doaj.art-bf46c66eb52d4858a4c5c3ef00d48bee |
| institution | Directory Open Access Journal |
| issn | 2195-8831 |
| language | English |
| last_indexed | 2024-12-11T13:34:37Z |
| publishDate | 2015-12-01 |
| publisher | German Medical Science GMS Publishing House |
| record_format | Article |
| series | GMS Infectious Diseases |
| spelling | doaj.art-bf46c66eb52d4858a4c5c3ef00d48bee2022-12-22T01:05:07ZengGerman Medical Science GMS Publishing HouseGMS Infectious Diseases2195-88312015-12-013Doc0310.3205/id000018Correlation of (1→3)-β-D-glucan with other inflammation markers in chronically HIV infected persons on suppressive antiretroviral therapyHoenigl, Martin0Faria de Oliveira, Michelli1Pérez-Santiago, Josué2Zhang, Yonglong3Woods, Steven Paul4Finkelman, Malcolm5Gianella, Sara6Division of Infectious Diseases, University of California San Diego, San Diego, California, USADivision of Infectious Diseases, University of California San Diego, San Diego, California, USADivision of Infectious Diseases, University of California San Diego, San Diego, California, USAResearch Laboratory, Associates of Cape Cod, Inc., Falmouth, Massachusetts, USADepartment of Psychology, University of Houston, Texas, USAResearch Laboratory, Associates of Cape Cod, Inc., Falmouth, Massachusetts, USADivision of Infectious Diseases, University of California San Diego, San Diego, California, USAWe evaluated associations between levels of BDG and other biomarkers of inflammation in blood from 41 virologically suppressed persons with chronic HIV-infection. We found a significant correlation between BDG and neopterin levels (r=0.68), and trends to significance for correlations with other inflammation markers (tumor-necrosis-factor-α: r=0.30; interleukin-8: r=0.30; interleukin-6: r=0.28). In conclusion, BDG levels correlated with inflammation markers in a cohort of virologically suppressed individuals with chronic HIV infection. Future studies are needed to evaluate whether BDG may be a marker for morbidity in chronic HIV infection.http://www.egms.de/static/en/journals/id/2015-3/id000018.shtmlbeta-D-glucanHIVvirologically suppressedneopterinplasmainterleukin |
| spellingShingle | Hoenigl, Martin Faria de Oliveira, Michelli Pérez-Santiago, Josué Zhang, Yonglong Woods, Steven Paul Finkelman, Malcolm Gianella, Sara Correlation of (1→3)-β-D-glucan with other inflammation markers in chronically HIV infected persons on suppressive antiretroviral therapy GMS Infectious Diseases beta-D-glucan HIV virologically suppressed neopterin plasma interleukin |
| title | Correlation of (1→3)-β-D-glucan with other inflammation markers in chronically HIV infected persons on suppressive antiretroviral therapy |
| title_full | Correlation of (1→3)-β-D-glucan with other inflammation markers in chronically HIV infected persons on suppressive antiretroviral therapy |
| title_fullStr | Correlation of (1→3)-β-D-glucan with other inflammation markers in chronically HIV infected persons on suppressive antiretroviral therapy |
| title_full_unstemmed | Correlation of (1→3)-β-D-glucan with other inflammation markers in chronically HIV infected persons on suppressive antiretroviral therapy |
| title_short | Correlation of (1→3)-β-D-glucan with other inflammation markers in chronically HIV infected persons on suppressive antiretroviral therapy |
| title_sort | correlation of 1 3 β d glucan with other inflammation markers in chronically hiv infected persons on suppressive antiretroviral therapy |
| topic | beta-D-glucan HIV virologically suppressed neopterin plasma interleukin |
| url | http://www.egms.de/static/en/journals/id/2015-3/id000018.shtml |
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