ANALISIS PROKSIMAT DAN TOKSISITAS AKUT EKSTRAK DAUN SIRIH MERAH YANG BERPOTENSI SEBAGAI ANTIDIABETES

The aim of this study was to explore the analysis proximate and toxicity of the decoctions of P. crocatum. Fresh leaves of P. crocatum were boiled in water in order to obtain decoction and were examined for its chemical compounds by using SNI 01-2891-1992 method for proximate analysis. Toxicity of d...

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Main Authors: Mega Safithri, Farah Fahma, Paramitha Wirdani Ningsih Marlina
Format: Article
Language:English
Published: Bogor Agricultural University 2012-03-01
Series:Jurnal Gizi dan Pangan
Subjects:
Online Access:https://jurnal.ipb.ac.id/index.php/jgizipangan/article/view/6141
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author Mega Safithri
Farah Fahma
Paramitha Wirdani Ningsih Marlina
author_facet Mega Safithri
Farah Fahma
Paramitha Wirdani Ningsih Marlina
author_sort Mega Safithri
collection DOAJ
description The aim of this study was to explore the analysis proximate and toxicity of the decoctions of P. crocatum. Fresh leaves of P. crocatum were boiled in water in order to obtain decoction and were examined for its chemical compounds by using SNI 01-2891-1992 method for proximate analysis. Toxicity of decoction extract of P. crocatum was orally fed to rats (Sprague dawley). The results showed that P. crocatum leaves contains 9.27% water, 14.33% ash, 3.96% fat, 22.63% proteins, and 59.08% carbohydrates. Acute toxicity test showed that all rats were still alive after 7 days treatment with P. crocatum decoction for all dose groups (0, 5, 10, and 20 g/kg BB). LC50 value of P. crocatum decoction was 544.82 ppm, meaning that the decoction was relatively harmless and bioactive.
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spelling doaj.art-bf4ab8320def47bd92f4b5e49d0060652023-09-29T06:29:55ZengBogor Agricultural UniversityJurnal Gizi dan Pangan1978-10592407-09202012-03-017110.25182/jgp.2012.7.1.43-49ANALISIS PROKSIMAT DAN TOKSISITAS AKUT EKSTRAK DAUN SIRIH MERAH YANG BERPOTENSI SEBAGAI ANTIDIABETESMega Safithri0Farah Fahma1Paramitha Wirdani Ningsih Marlina2Departemen Biokimia, Fakultas Matematika dan IPA (FMIPA), Institut Pertanian BogorDepartemen Teknologi Industri Pertanian, Fakultas Teknologi Pertanian (FATETA), Institut Pertanian BogorDepartemen Biokimia, Fakultas Matematika dan IPA (FMIPA), Institut Pertanian BogorThe aim of this study was to explore the analysis proximate and toxicity of the decoctions of P. crocatum. Fresh leaves of P. crocatum were boiled in water in order to obtain decoction and were examined for its chemical compounds by using SNI 01-2891-1992 method for proximate analysis. Toxicity of decoction extract of P. crocatum was orally fed to rats (Sprague dawley). The results showed that P. crocatum leaves contains 9.27% water, 14.33% ash, 3.96% fat, 22.63% proteins, and 59.08% carbohydrates. Acute toxicity test showed that all rats were still alive after 7 days treatment with P. crocatum decoction for all dose groups (0, 5, 10, and 20 g/kg BB). LC50 value of P. crocatum decoction was 544.82 ppm, meaning that the decoction was relatively harmless and bioactive. https://jurnal.ipb.ac.id/index.php/jgizipangan/article/view/6141Piper crocatumproximate analysistoxicityantidiabetic
spellingShingle Mega Safithri
Farah Fahma
Paramitha Wirdani Ningsih Marlina
ANALISIS PROKSIMAT DAN TOKSISITAS AKUT EKSTRAK DAUN SIRIH MERAH YANG BERPOTENSI SEBAGAI ANTIDIABETES
Jurnal Gizi dan Pangan
Piper crocatum
proximate analysis
toxicity
antidiabetic
title ANALISIS PROKSIMAT DAN TOKSISITAS AKUT EKSTRAK DAUN SIRIH MERAH YANG BERPOTENSI SEBAGAI ANTIDIABETES
title_full ANALISIS PROKSIMAT DAN TOKSISITAS AKUT EKSTRAK DAUN SIRIH MERAH YANG BERPOTENSI SEBAGAI ANTIDIABETES
title_fullStr ANALISIS PROKSIMAT DAN TOKSISITAS AKUT EKSTRAK DAUN SIRIH MERAH YANG BERPOTENSI SEBAGAI ANTIDIABETES
title_full_unstemmed ANALISIS PROKSIMAT DAN TOKSISITAS AKUT EKSTRAK DAUN SIRIH MERAH YANG BERPOTENSI SEBAGAI ANTIDIABETES
title_short ANALISIS PROKSIMAT DAN TOKSISITAS AKUT EKSTRAK DAUN SIRIH MERAH YANG BERPOTENSI SEBAGAI ANTIDIABETES
title_sort analisis proksimat dan toksisitas akut ekstrak daun sirih merah yang berpotensi sebagai antidiabetes
topic Piper crocatum
proximate analysis
toxicity
antidiabetic
url https://jurnal.ipb.ac.id/index.php/jgizipangan/article/view/6141
work_keys_str_mv AT megasafithri analisisproksimatdantoksisitasakutekstrakdaunsirihmerahyangberpotensisebagaiantidiabetes
AT farahfahma analisisproksimatdantoksisitasakutekstrakdaunsirihmerahyangberpotensisebagaiantidiabetes
AT paramithawirdaniningsihmarlina analisisproksimatdantoksisitasakutekstrakdaunsirihmerahyangberpotensisebagaiantidiabetes