ANALISIS PROKSIMAT DAN TOKSISITAS AKUT EKSTRAK DAUN SIRIH MERAH YANG BERPOTENSI SEBAGAI ANTIDIABETES
The aim of this study was to explore the analysis proximate and toxicity of the decoctions of P. crocatum. Fresh leaves of P. crocatum were boiled in water in order to obtain decoction and were examined for its chemical compounds by using SNI 01-2891-1992 method for proximate analysis. Toxicity of d...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Bogor Agricultural University
2012-03-01
|
Series: | Jurnal Gizi dan Pangan |
Subjects: | |
Online Access: | https://jurnal.ipb.ac.id/index.php/jgizipangan/article/view/6141 |
_version_ | 1797671354265239552 |
---|---|
author | Mega Safithri Farah Fahma Paramitha Wirdani Ningsih Marlina |
author_facet | Mega Safithri Farah Fahma Paramitha Wirdani Ningsih Marlina |
author_sort | Mega Safithri |
collection | DOAJ |
description | The aim of this study was to explore the analysis proximate and toxicity of the decoctions of P. crocatum. Fresh leaves of P. crocatum were boiled in water in order to obtain decoction and were examined for its chemical compounds by using SNI 01-2891-1992 method for proximate analysis. Toxicity of decoction extract of P. crocatum was orally fed to rats (Sprague dawley). The results showed that P. crocatum leaves contains 9.27% water, 14.33% ash, 3.96% fat, 22.63% proteins, and 59.08% carbohydrates. Acute toxicity test showed that all rats were still alive after 7 days treatment with P. crocatum decoction for all dose groups (0, 5, 10, and 20 g/kg BB). LC50 value of P. crocatum decoction was 544.82 ppm, meaning that the decoction was relatively harmless and bioactive.
|
first_indexed | 2024-03-11T21:13:08Z |
format | Article |
id | doaj.art-bf4ab8320def47bd92f4b5e49d006065 |
institution | Directory Open Access Journal |
issn | 1978-1059 2407-0920 |
language | English |
last_indexed | 2024-03-11T21:13:08Z |
publishDate | 2012-03-01 |
publisher | Bogor Agricultural University |
record_format | Article |
series | Jurnal Gizi dan Pangan |
spelling | doaj.art-bf4ab8320def47bd92f4b5e49d0060652023-09-29T06:29:55ZengBogor Agricultural UniversityJurnal Gizi dan Pangan1978-10592407-09202012-03-017110.25182/jgp.2012.7.1.43-49ANALISIS PROKSIMAT DAN TOKSISITAS AKUT EKSTRAK DAUN SIRIH MERAH YANG BERPOTENSI SEBAGAI ANTIDIABETESMega Safithri0Farah Fahma1Paramitha Wirdani Ningsih Marlina2Departemen Biokimia, Fakultas Matematika dan IPA (FMIPA), Institut Pertanian BogorDepartemen Teknologi Industri Pertanian, Fakultas Teknologi Pertanian (FATETA), Institut Pertanian BogorDepartemen Biokimia, Fakultas Matematika dan IPA (FMIPA), Institut Pertanian BogorThe aim of this study was to explore the analysis proximate and toxicity of the decoctions of P. crocatum. Fresh leaves of P. crocatum were boiled in water in order to obtain decoction and were examined for its chemical compounds by using SNI 01-2891-1992 method for proximate analysis. Toxicity of decoction extract of P. crocatum was orally fed to rats (Sprague dawley). The results showed that P. crocatum leaves contains 9.27% water, 14.33% ash, 3.96% fat, 22.63% proteins, and 59.08% carbohydrates. Acute toxicity test showed that all rats were still alive after 7 days treatment with P. crocatum decoction for all dose groups (0, 5, 10, and 20 g/kg BB). LC50 value of P. crocatum decoction was 544.82 ppm, meaning that the decoction was relatively harmless and bioactive. https://jurnal.ipb.ac.id/index.php/jgizipangan/article/view/6141Piper crocatumproximate analysistoxicityantidiabetic |
spellingShingle | Mega Safithri Farah Fahma Paramitha Wirdani Ningsih Marlina ANALISIS PROKSIMAT DAN TOKSISITAS AKUT EKSTRAK DAUN SIRIH MERAH YANG BERPOTENSI SEBAGAI ANTIDIABETES Jurnal Gizi dan Pangan Piper crocatum proximate analysis toxicity antidiabetic |
title | ANALISIS PROKSIMAT DAN TOKSISITAS AKUT EKSTRAK DAUN SIRIH MERAH YANG BERPOTENSI SEBAGAI ANTIDIABETES |
title_full | ANALISIS PROKSIMAT DAN TOKSISITAS AKUT EKSTRAK DAUN SIRIH MERAH YANG BERPOTENSI SEBAGAI ANTIDIABETES |
title_fullStr | ANALISIS PROKSIMAT DAN TOKSISITAS AKUT EKSTRAK DAUN SIRIH MERAH YANG BERPOTENSI SEBAGAI ANTIDIABETES |
title_full_unstemmed | ANALISIS PROKSIMAT DAN TOKSISITAS AKUT EKSTRAK DAUN SIRIH MERAH YANG BERPOTENSI SEBAGAI ANTIDIABETES |
title_short | ANALISIS PROKSIMAT DAN TOKSISITAS AKUT EKSTRAK DAUN SIRIH MERAH YANG BERPOTENSI SEBAGAI ANTIDIABETES |
title_sort | analisis proksimat dan toksisitas akut ekstrak daun sirih merah yang berpotensi sebagai antidiabetes |
topic | Piper crocatum proximate analysis toxicity antidiabetic |
url | https://jurnal.ipb.ac.id/index.php/jgizipangan/article/view/6141 |
work_keys_str_mv | AT megasafithri analisisproksimatdantoksisitasakutekstrakdaunsirihmerahyangberpotensisebagaiantidiabetes AT farahfahma analisisproksimatdantoksisitasakutekstrakdaunsirihmerahyangberpotensisebagaiantidiabetes AT paramithawirdaniningsihmarlina analisisproksimatdantoksisitasakutekstrakdaunsirihmerahyangberpotensisebagaiantidiabetes |